Please use this identifier to cite or link to this item: https://doi.org/10.1017/S0033291717003154
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dc.titleDirectional associations between memory impairment and depressive symptoms: data from a longitudinal sample and meta-analysis
dc.contributor.authorYU JUNHONG
dc.contributor.authorLim, Hui-Ying
dc.contributor.authorFADZILLAH NUR D/O MOHAMED ABDULLAH
dc.contributor.authorCHAN HUI MINN
dc.contributor.authorRATHI MAHENDRAN
dc.contributor.authorROGER HO CHUN MAN
dc.contributor.authorKUA EE HEOK
dc.contributor.authorPOWER, MICHAEL JOHN
dc.contributor.authorFeng Lei
dc.date.accessioned2020-08-31T02:34:27Z
dc.date.available2020-08-31T02:34:27Z
dc.date.issued2018-07-01
dc.identifier.citationYU JUNHONG, Lim, Hui-Ying, FADZILLAH NUR D/O MOHAMED ABDULLAH, CHAN HUI MINN, RATHI MAHENDRAN, ROGER HO CHUN MAN, KUA EE HEOK, POWER, MICHAEL JOHN, Feng Lei (2018-07-01). Directional associations between memory impairment and depressive symptoms: data from a longitudinal sample and meta-analysis. PSYCHOLOGICAL MEDICINE 48 (10) : 1664-1672. ScholarBank@NUS Repository. https://doi.org/10.1017/S0033291717003154
dc.identifier.issn0033-2917
dc.identifier.issn1469-8978
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/173635
dc.description.abstractBackground: Previous cross-lagged studies on depression and memory impairment among the elderly have revealed conflicting findings relating to the direction of influence between depression and memory impairment. The current study aims to clarify this direction of influence by examining the cross-lagged relationships between memory impairment and depression in an Asian sample of elderly community dwellers, as well as synthesizing previous relevant cross-lagged findings via a meta-analysis. Methods: A total of 160 participants (Mage = 68.14, s.d. = 5.34) were assessed across two time points (average of 1.9 years apart) on measures of memory and depressive symptoms. The data were then fitted to a structural equation model to examine two cross-lagged effects (i.e. depressive symptoms→memory; memory→depressive symptoms). A total of 14 effect-sizes for each of the two cross-lagged directions were extracted from six studies (including the present; total N = 8324). These effects were then meta-analyzed using a three-level mixed effects model. Results: In the current sample, lower memory ability at baseline was associated with worse depressive symptoms levels at follow-up, after controlling for baseline depressive symptoms. However, the reverse effect was not significant; baseline depressive symptoms did not predict subsequent memory ability after controlling for baseline memory. The results of the meta-analysis revealed the same pattern of relationship between memory and depressive symptoms. Conclusions: These results provide robust evidence that the relationship between memory impairment and depressive symptoms is unidirectional; memory impairment predicts subsequent depressive symptoms but not vice-versa. The implications of these findings are discussed.
dc.language.isoen
dc.publisherCAMBRIDGE UNIV PRESS
dc.sourceElements
dc.subjectSocial Sciences
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectPsychology, Clinical
dc.subjectPsychiatry
dc.subjectPsychology
dc.subjectAging
dc.subjectcross-lagged
dc.subjectdepression
dc.subjectlongitudinal
dc.subjectmemory
dc.subjectMILD COGNITIVE IMPAIRMENT
dc.subjectLATE-LIFE DEPRESSION
dc.subjectOLDER-ADULTS
dc.subjectRISK-FACTORS
dc.subjectDEMENTIA
dc.subjectPREVALENCE
dc.subjectVITAMIN-B-12
dc.subjectPERFORMANCE
dc.subjectDISORDER
dc.subjectDECLINE
dc.typeArticle
dc.date.updated2020-08-28T07:59:30Z
dc.contributor.departmentDEPT OF PSYCHOLOGICAL MEDICINE
dc.contributor.departmentDEPT OF PSYCHOLOGY
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.description.doi10.1017/S0033291717003154
dc.description.sourcetitlePSYCHOLOGICAL MEDICINE
dc.description.volume48
dc.description.issue10
dc.description.page1664-1672
dc.published.statePublished
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