Please use this identifier to cite or link to this item: https://doi.org/10.1017/S1355617719001206
Title: Multi-Session Anodal Prefrontal Transcranial Direct Current Stimulation does not Improve Executive Functions among Older Adults
Authors: YU JUNHONG 
Lam, Charlene LM
Man, Idy SC
Shao, Robin
Lee, Tatia MC
Keywords: Science & Technology
Social Sciences
Life Sciences & Biomedicine
Clinical Neurology
Neurosciences
Psychiatry
Psychology
Neurosciences & Neurology
tDCS
Intervention
Executive functions
Aging
COGNITIVE FUNCTION
HEALTHY
BRAIN
TDCS
METAANALYSIS
DEMENTIA
CORTEX
MEMORY
TRAIL
TESTS
Issue Date: 1-Apr-2020
Publisher: CAMBRIDGE UNIV PRESS
Citation: YU JUNHONG, Lam, Charlene LM, Man, Idy SC, Shao, Robin, Lee, Tatia MC (2020-04-01). Multi-Session Anodal Prefrontal Transcranial Direct Current Stimulation does not Improve Executive Functions among Older Adults. Journal of the International Neuropsychological Society 26 (4) : 372-381. ScholarBank@NUS Repository. https://doi.org/10.1017/S1355617719001206
Abstract: Objective: Findings from single-session online studies highlighted the potential of using anodal prefrontal transcranial direct current stimulation (tDCS) to enhance executive functions (EF) in the context of aging. However, tDCS must be executed as a multi-session offline intervention to ascertain its viability in this context. Relatedly, findings from multi-session studies remained inconclusive. To this end, we examined the effects of multi-session anodal prefrontal tDCS on EF in an intervention.Method: The intervention consisted of 15 sessions; in each, healthy older participants (Agemean = 66.7) received either 15 min of 1.5 mA tDCS (Ncompleted = 35) or sham stimulation (Ncompleted = 33) while performing EF training tasks. EF measures were assessed at baseline, post-intervention, and 1-month follow-up. Hierarchical linear models were used to examine the effect of tDCS on EF outcomes.Results: Both groups of participants did not differ significantly in side effect ratings and attendance. There were no significant tDCS-associated gains in any EF outcomes in the intervention.Conclusions: Multi-session prefrontal tDCS did not lead to any significant gains in EF in the current intervention. More research is needed to optimize the use of tDCS before it can be effectively used to enhance EF among older adults.
Source Title: Journal of the International Neuropsychological Society
URI: https://scholarbank.nus.edu.sg/handle/10635/173573
ISBN: 1469-7661
ISSN: 1355-6177
DOI: 10.1017/S1355617719001206
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