Please use this identifier to cite or link to this item: https://doi.org/10.1111/ceo.12974
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dc.titleSingapore Indian Eye Study-2: methodology and impact of migration on systemic and eye outcomes
dc.contributor.authorSabanayagam, Charumathi
dc.contributor.authorYip, Wanfen
dc.contributor.authorGupta, Preeti
dc.contributor.authorAbdul, Riswana BB Mohd
dc.contributor.authorLamoureux, Ecosse
dc.contributor.authorKumari, Neelam
dc.contributor.authorCheung, Gemmy CM
dc.contributor.authorCheung, Carol Y
dc.contributor.authorWang, Jie Jin
dc.contributor.authorCheng, Ching-Yu
dc.contributor.authorWong, Tien Yin
dc.date.accessioned2020-08-20T23:58:44Z
dc.date.available2020-08-20T23:58:44Z
dc.date.issued2017-11-01
dc.identifier.citationSabanayagam, Charumathi, Yip, Wanfen, Gupta, Preeti, Abdul, Riswana BB Mohd, Lamoureux, Ecosse, Kumari, Neelam, Cheung, Gemmy CM, Cheung, Carol Y, Wang, Jie Jin, Cheng, Ching-Yu, Wong, Tien Yin (2017-11-01). Singapore Indian Eye Study-2: methodology and impact of migration on systemic and eye outcomes. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 45 (8) : 779-789. ScholarBank@NUS Repository. https://doi.org/10.1111/ceo.12974
dc.identifier.issn14426404
dc.identifier.issn14429071
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/173198
dc.description.abstract© 2017 Royal Australian and New Zealand College of Ophthalmologists Importance: Asian Indians are the fastest growing migration groups in the world. Studies evaluating the impact of migration on disease outcomes in this population are rare. Background: We describe the methodology of the Singapore Indian Eye Study-2 (SINDI-2) aimed to evaluate the impact of migration status on diabetic retinopathy and other major age-related eye diseases in Asian Indians living in an urban environment. Design: Population-based cohort study. Participants: A total of 2200 adults had participated in baseline SINDI (2007–2009, mean age [range] = 57.8 [42.7–84.1] years) and SINDI-2 (2013–2015, 56.5 [48.4–90.2] years). Methods: Participants were classified as ‘first generation’ if they were Indian residents born outside of Singapore and as ‘second-generation’ immigrants (59.7% in SINDI vs. 63.6% in SINDI-2) if they were born in Singapore. Main Outcome Measures: Response rate, participant characteristics and prevalence of systemic diseases were stratified by migration status. Results: Of the 2914 eligible SINDI participants invited to participate, 2200 participated in SINDI-2 (response rate of 75.2%). In both SINDI and SINDI-2, compared with first-generation immigrants, second-generation immigrants were younger, less likely to have income <1000 SGD, had lower levels of pulse pressure, higher levels of high-density lipoprotein cholesterol, had lower prevalence of hypertension and chronic kidney disease and had higher prevalence of current smoking and obesity (all P < 0.05). Conclusions and Relevance: In both SINDI and SINDI-2, second-generation immigrants had lower prevalence of cardiovascular risk factors except smoking and obesity compared with first-generation immigrants. The final report will confirm if these differences between generations are evident with regard to eye diseases.
dc.language.isoen
dc.publisherWILEY
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectOphthalmology
dc.subjectAsian Indians
dc.subjectassociation
dc.subjectdiabetic retinopathy
dc.subjectincidence
dc.subjectprogression
dc.subjectPOPULATION-BASED ASSESSMENT
dc.subjectURBAN-RURAL EPIDEMIOLOGY
dc.subjectOBSTRUCTIVE SLEEP-APNEA
dc.subjectDIABETIC-RETINOPATHY
dc.subjectVISUAL IMPAIRMENT
dc.subjectRISK-FACTORS
dc.subjectSOUTHERN INDIA
dc.subjectUNITED-STATES
dc.subjectPREVALENCE
dc.subjectDISEASE
dc.typeArticle
dc.date.updated2020-06-03T13:43:26Z
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.description.doi10.1111/ceo.12974
dc.description.sourcetitleCLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
dc.description.volume45
dc.description.issue8
dc.description.page779-789
dc.published.statePublished
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