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https://doi.org/10.1111/ceo.12974
Title: | Singapore Indian Eye Study-2: methodology and impact of migration on systemic and eye outcomes | Authors: | Sabanayagam, Charumathi Yip, Wanfen Gupta, Preeti Abdul, Riswana BB Mohd Lamoureux, Ecosse Kumari, Neelam Cheung, Gemmy CM Cheung, Carol Y Wang, Jie Jin Cheng, Ching-Yu Wong, Tien Yin |
Keywords: | Science & Technology Life Sciences & Biomedicine Ophthalmology Asian Indians association diabetic retinopathy incidence progression POPULATION-BASED ASSESSMENT URBAN-RURAL EPIDEMIOLOGY OBSTRUCTIVE SLEEP-APNEA DIABETIC-RETINOPATHY VISUAL IMPAIRMENT RISK-FACTORS SOUTHERN INDIA UNITED-STATES PREVALENCE DISEASE |
Issue Date: | 1-Nov-2017 | Publisher: | WILEY | Citation: | Sabanayagam, Charumathi, Yip, Wanfen, Gupta, Preeti, Abdul, Riswana BB Mohd, Lamoureux, Ecosse, Kumari, Neelam, Cheung, Gemmy CM, Cheung, Carol Y, Wang, Jie Jin, Cheng, Ching-Yu, Wong, Tien Yin (2017-11-01). Singapore Indian Eye Study-2: methodology and impact of migration on systemic and eye outcomes. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 45 (8) : 779-789. ScholarBank@NUS Repository. https://doi.org/10.1111/ceo.12974 | Abstract: | © 2017 Royal Australian and New Zealand College of Ophthalmologists Importance: Asian Indians are the fastest growing migration groups in the world. Studies evaluating the impact of migration on disease outcomes in this population are rare. Background: We describe the methodology of the Singapore Indian Eye Study-2 (SINDI-2) aimed to evaluate the impact of migration status on diabetic retinopathy and other major age-related eye diseases in Asian Indians living in an urban environment. Design: Population-based cohort study. Participants: A total of 2200 adults had participated in baseline SINDI (2007–2009, mean age [range] = 57.8 [42.7–84.1] years) and SINDI-2 (2013–2015, 56.5 [48.4–90.2] years). Methods: Participants were classified as ‘first generation’ if they were Indian residents born outside of Singapore and as ‘second-generation’ immigrants (59.7% in SINDI vs. 63.6% in SINDI-2) if they were born in Singapore. Main Outcome Measures: Response rate, participant characteristics and prevalence of systemic diseases were stratified by migration status. Results: Of the 2914 eligible SINDI participants invited to participate, 2200 participated in SINDI-2 (response rate of 75.2%). In both SINDI and SINDI-2, compared with first-generation immigrants, second-generation immigrants were younger, less likely to have income <1000 SGD, had lower levels of pulse pressure, higher levels of high-density lipoprotein cholesterol, had lower prevalence of hypertension and chronic kidney disease and had higher prevalence of current smoking and obesity (all P < 0.05). Conclusions and Relevance: In both SINDI and SINDI-2, second-generation immigrants had lower prevalence of cardiovascular risk factors except smoking and obesity compared with first-generation immigrants. The final report will confirm if these differences between generations are evident with regard to eye diseases. | Source Title: | CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY | URI: | https://scholarbank.nus.edu.sg/handle/10635/173198 | ISSN: | 14426404 14429071 |
DOI: | 10.1111/ceo.12974 |
Appears in Collections: | Staff Publications Elements |
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