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https://doi.org/10.1002/smll.201201363
| Title: | Exposure to Titanium Dioxide Nanoparticles Induces Autophagy in Primary Human Keratinocytes | Authors: | Zhao, Yun Howe, Josephine LC Yu, Zhang: Leong, David Tai Chu, Justin Jang Hann Loo, Joachim Say Chye Ng, Kee Woei |
Keywords: | Science & Technology Physical Sciences Technology Chemistry, Multidisciplinary Chemistry, Physical Nanoscience & Nanotechnology Materials Science, Multidisciplinary Physics, Applied Physics, Condensed Matter Chemistry Science & Technology - Other Topics Materials Science Physics autophagy titanium dioxide nanoparticles nanotoxicology keratinocytes TIO2 NANOPARTICLES SUNSCREEN FORMULATIONS KIDNEY-CELLS IN-VITRO SKIN PARTICLES SAFETY NANOTECHNOLOGY CYTOTOXICITY PENETRATION |
Issue Date: | 11-Feb-2013 | Publisher: | WILEY-V C H VERLAG GMBH | Citation: | Zhao, Yun, Howe, Josephine LC, Yu, Zhang:, Leong, David Tai, Chu, Justin Jang Hann, Loo, Joachim Say Chye, Ng, Kee Woei (2013-02-11). Exposure to Titanium Dioxide Nanoparticles Induces Autophagy in Primary Human Keratinocytes. SMALL 9 (3) : 387-392. ScholarBank@NUS Repository. https://doi.org/10.1002/smll.201201363 | Abstract: | Understanding the mechanisms of cell-nanomaterial interactions is vital in harnessing the potential of using nanomaterials in biomedical applications. By immuno-labeling of LC3 and TEM analysis, it is found that titanium dioxide nanoparticles are internalized by human keratinocytes and induce autophagy. Autophagy appears to play a cytoprotective role in response to toxicity influence exerted by the nanoparticles. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | Source Title: | SMALL | URI: | https://scholarbank.nus.edu.sg/handle/10635/173125 | ISSN: | 16136810 16136829 |
DOI: | 10.1002/smll.201201363 |
| Appears in Collections: | Staff Publications Elements |
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