Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/16146
DC FieldValue
dc.titleA fMRI study of the brain activity as a function of total sleep deprivation and circadian rhythmicity
dc.contributor.authorLEE WEI WEI
dc.date.accessioned2010-04-08T11:01:33Z
dc.date.available2010-04-08T11:01:33Z
dc.date.issued2007-04-19
dc.identifier.citationLEE WEI WEI (2007-04-19). A fMRI study of the brain activity as a function of total sleep deprivation and circadian rhythmicity. ScholarBank@NUS Repository.
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/16146
dc.description.abstractSleep deprivation significantly impairs human cognitive functioning. The cerebral response to sleep deprivation was examined with functional magnetic resonance imaging (fMRI) on 16 subjects to monitor brain activity across 24 hr. The tone task found activations in the left precentral gyrus, thalamus, bilateral medial frontal cortex, right superior temporal gyrus and left substantia nigra while the numbers task found activations in the left precentral gyrus, right medial frontal gyrus, right middle frontal gyrus, left superior temporal gyrus, right postcentral gyrus, right inferior parietal gyrus, bilateral ACC and bilateral thalamus. The effects of total sleep deprivation (TSD) were most acute in the superior temporal gyrus, suggesting a predisposition to the effects of total sleep deprivation as well as its role as an indicator of task performance. The inferior parietal lobes and the thalamus may be part of a compensatory response undertaken by the brain to counter the effects of sleep deprivation.
dc.language.isoen
dc.subjectfMRI, brain, sleep, deprivation, cognition, auditory
dc.typeThesis
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.contributor.supervisorSHEU FWU-SHAN
dc.description.degreeMaster's
dc.description.degreeconferredMASTER OF SCIENCE
dc.identifier.isiutNOT_IN_WOS
Appears in Collections:Master's Theses (Open)

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
01_LeeWW.pdf6.52 kBAdobe PDF

OPEN

NoneView/Download
02_LeeWW.pdf25.92 kBAdobe PDF

OPEN

NoneView/Download
03_LeeWW.pdf269.95 kBAdobe PDF

OPEN

NoneView/Download
04_LeeWW.pdf213.21 kBAdobe PDF

OPEN

NoneView/Download

Page view(s)

418
checked on May 18, 2019

Download(s)

604
checked on May 18, 2019

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.