Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0079860
Title: RPS8 - A new informative DNA marker for phylogeny of Babesia and Theileria parasites in China
Authors: Tian Z.-C.
Liu G.-Y.
Yin H.
Luo J.-X.
Guan G.-Q.
Luo J.
Xie J.-R.
Shen H. 
Tian M.-Y.
Zheng J.-F.
Yuan X.-S.
Wang F.-F.
Keywords: DNA 18S
40S ribosomal protein S8 gene
article
Babesia
China
controlled study
DNA marker
DNA sequence
exon
gene sequence
genetic distance
intraspecific variation
intron
molecular phylogeny
nonhuman
nucleotide sequence
phylogenetic tree
Theileria
Animals
Babesia
Base Sequence
Cattle
China
DNA, Protozoan
Exons
Genetic Markers
Humans
Introns
Molecular Sequence Data
Open Reading Frames
Phylogeny
Protozoan Proteins
Ribosomal Proteins
Ribosome Subunits, Small, Eukaryotic
Theileria
Issue Date: 2013
Citation: Tian Z.-C., Liu G.-Y., Yin H., Luo J.-X., Guan G.-Q., Luo J., Xie J.-R., Shen H., Tian M.-Y., Zheng J.-F., Yuan X.-S., Wang F.-F. (2013). RPS8 - A new informative DNA marker for phylogeny of Babesia and Theileria parasites in China. PLoS ONE 8 (11) : e79860. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0079860
Abstract: Piroplasmosis is a serious debilitating and sometimes fatal disease. Phylogenetic relationships within piroplasmida are complex and remain unclear. We compared the intron-exon structure and DNA sequences of the RPS8 gene from Babesia and Theileria spp. isolates in China. Similar to 18S rDNA, the 40S ribosomal protein S8 gene, RPS8, including both coding and non-coding regions is a useful and novel genetic marker for defining species boundaries and for inferring phylogenies because it tends to have little intra-specific variation but considerable inter-specific difference. However, more samples are needed to verify the usefulness of the RPS8 (coding and non-coding regions) gene as a marker for the phylogenetic position and detection of most Babesia and Theileria species, particularly for some closely related species. © 2013 Tian et al.
Source Title: PLoS ONE
URI: https://scholarbank.nus.edu.sg/handle/10635/161456
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0079860
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