Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/157757
Title: A COMPARATIVE ANALYSIS OF AGE AND TD AND ITS EFFECTS ON PROCEDURAL LEARNING IN SINGAPOREANS
Authors: YEO SHERWYNN
Keywords: Tardive Dyskinesia
Schizophrenia
Age
Procedural Learning
Issue Date: 4-Dec-2019
Citation: YEO SHERWYNN (2019-12-04). A COMPARATIVE ANALYSIS OF AGE AND TD AND ITS EFFECTS ON PROCEDURAL LEARNING IN SINGAPOREANS. ScholarBank@NUS Repository.
Abstract: Tardive dyskinesia (TD) is an iatrogenic movement disorder that develops due to prolonged antipsychotic consumption in individuals with psychosis such as schizophrenia. Advanced age is a significant risk factor for TD, and both age and TD have their effects on procedural learning. This thesis sought to investigate how age affects TD, which consequently affects one's procedural learning. It comprehensively analyses the effects of age on TD and its subsequent effects on procedural learning using the Pursuit Rotor Task, further investigating a critical mediating factor of mental processing speed using measures on the Symbol Digit modality Test. This was conducted on 52 Singaporean individuals, 32 diagnosed with schizophrenia, of which 15 had definite TD. Patients with TD revealed to have significant procedural learning deficits, and age was not found to be a significant factor. The relationship between TD and procedural learning could be partially explained by mental processing speed. This highlights the neurocognitive deficits that results from TD on top of the involuntary movements, stressing the importance of prevention of development. As for age, there were several limitations potentially accounting for the divergent results from existing literature. Thus, the results from this study should be considered with a degree of discretion.
URI: https://scholarbank.nus.edu.sg/handle/10635/157757
Appears in Collections:Bachelor's Theses

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