Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.celrep.2019.02.083
Title: In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors
Authors: Yap, Lynn
Wang, Jiong-Wei 
Moreno-Moral, Aida 
Chong, Li Yen 
Sun, Yi
Harmston, Nathan 
Wang, Xiaoyuan 
Chong, Suet Yen 
Ohman, Miina K 
Wei, Heming 
Bunte, Ralph 
Gosh, Sujoy
Cook, Stuart 
Hovatta, Outi
de Kleijn, Dominique P
Petretto, Enrico 
Tryggvason, Karl 
Keywords: Science & Technology
Life Sciences & Biomedicine
Cell Biology
PLURIPOTENT STEM-CELLS
TERM SELF-RENEWAL
CARDIOMYOCYTE DIFFERENTIATION
HUMAN FIBROBLASTS
HEART
EXPRESSION
REPAIR
TRANSPLANTATION
PURIFICATION
REGENERATION
Issue Date: 19-Mar-2019
Publisher: CELL PRESS
Citation: Yap, Lynn, Wang, Jiong-Wei, Moreno-Moral, Aida, Chong, Li Yen, Sun, Yi, Harmston, Nathan, Wang, Xiaoyuan, Chong, Suet Yen, Ohman, Miina K, Wei, Heming, Bunte, Ralph, Gosh, Sujoy, Cook, Stuart, Hovatta, Outi, de Kleijn, Dominique P, Petretto, Enrico, Tryggvason, Karl (2019-03-19). In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors. CELL REPORTS 26 (12) : 3231-+. ScholarBank@NUS Repository. https://doi.org/10.1016/j.celrep.2019.02.083
Abstract: © 2019 The Author(s) Yap et al. perform in vitro differentiation of pluripotent embryonic stem cells to cardiovascular progenitors using laminin-221 as a culture matrix in a fully human and chemically defined protocol. Use of these cells for in vivo cardiac regeneration and to generate human heart muscle bundles results in improved heart function.
Source Title: CELL REPORTS
URI: https://scholarbank.nus.edu.sg/handle/10635/155366
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2019.02.083
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