Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/153846
Title: EFFECTS OF PREHABILITATION ON QUALITY OF LIFE AND RECOVERY IN LUNG CANCER PATIENTS : A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: DAPHNE CHEONG YU BING
Keywords: lung cancer
prehabilitation
quality of life
postoperative length of stay
6-minute walk distance
Issue Date: 25-May-2019
Citation: DAPHNE CHEONG YU BING (2019-05-25). EFFECTS OF PREHABILITATION ON QUALITY OF LIFE AND RECOVERY IN LUNG CANCER PATIENTS : A SYSTEMATIC REVIEW AND META-ANALYSIS. ScholarBank@NUS Repository.
Abstract: Background: While surgical resection is highly sought for operable lung cancer, it is associated with risks of unfavorable postsurgical outcomes including increased postoperative complications, delayed hospital discharge and deterioration in physical fitness. Aims: The primary aims of this review were to investigate the efficacy of prehabilitation on postoperative hospitalization duration, incidence of postsurgical complications, health-related quality of life (HRQOL) and 6-minute walking distance (6MWD) in lung cancer patients. Secondary outcomes evaluated were days with chest tube and incidence of specific pulmonary complications – pneumonia, atelectasis and respiratory failure. Methods: A literature search was conducted in Cochrane, EMBASE, PubMed, CINAHL, PsycInfo, ScienceDirect, Scopus, and Web of Science databases for randomized controlled trials within the past 10 years. We used meta-analysis as well as additional methods of sensitivity analysis and subgroup analysis where appropriate. Results: Our results show significant benefits in decreasing postoperative length of stay (LOS) (SMD= -0.62 CI -0.85, -0.40), improving postoperative mean 6MWD scores (SMD= -0.46 CI -0.87, -0.04) and decreasing days with chest tube (SMD= -1.04 CI -1.73, -0.35). Global QOL (SMD= 0.16 CI -0.11, 0.42) and subsets of physical function, emotional function and dyspnea score were clinically insignificant. Incidence of postoperative complications was not reduced despite subgrouping into general complications (RR= 1.14 CI 0.39, 3.36) and pulmonary complications (RR= 0.98 CI 0.77, 1.25). Pneumonia, atelectasis and respiratory failure did not experience a decrease in incidence after prehabilitative interventions. Conclusions: Initiating prehabilitation benefits postoperative recovery of lung cancer patients by decreasing postoperative LOS, improving physical function in terms of mean 6MWD scores and decreases the duration of chest tube inserted. Implications: This encourages hospitals to conduct prehabilitative programs for lung cancer patients, supervising intense activities while empowering patients with self-regulation opportunities.
URI: https://scholarbank.nus.edu.sg/handle/10635/153846
Appears in Collections:Bachelor's Theses

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
DAPHNE CHEONG YU BING_A0159990L.pdf808.65 kBAdobe PDF

RESTRICTED

NoneLog In

Page view(s)

25
checked on Jul 3, 2020

Download(s)

6
checked on Jul 3, 2020

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.