Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/153797
Title: EXAMINING RISK FACTORS ASSOICATED WITH SURGICAL SITE INFECTIONS IN BREAST CANCER PATIENTS: A RETROSPECTIVE CASE RECORD REVIEW
Authors: RACHEL TAN ZHAO FANG
Keywords: Breast Cancer
Surgical Site Infection
Risk Factors
Retrospective
Case-control Study
Issue Date: 25-May-2019
Citation: RACHEL TAN ZHAO FANG (2019-05-25). EXAMINING RISK FACTORS ASSOICATED WITH SURGICAL SITE INFECTIONS IN BREAST CANCER PATIENTS: A RETROSPECTIVE CASE RECORD REVIEW. ScholarBank@NUS Repository.
Abstract: Background: Surgical excisions are the frontline of curative treatment for breast cancer. An emphasis on minimising surgical site infections (SSI) during the post-operative phase is indispensable, particularly to minimise burdens on individuals and institutions. To date, no local study has consolidated factors associated with breast SSI, which provides an impetus for these factors to be examined in the Singapore context. Aims: This study aims to identify all factors associated with and predictive of SSI development among breast cancer surgical patients. Methods: This case-control study adopted a retrospective medical record review of breast cancer surgery patients from January 2013 to December 2016. The study's sampling frame included 21 cases with clinically diagnosed breast SSI and/or positive wound cultures within a year of surgery. For every one case selected, four controls (n=84) will matched according to their age at the time of operation. Chi-square test and Mann-Whitney U test were used to identify risk factors significantly associated with SSIs. Analysis of predictive variables with a multiple regression included factors with p-values<0.20 in the univariate analyses. Results: With the data retrieved, the prevalence of breast SSI was found to be 9%. From the univariate analysis, four independent variables were identified to be significantly associated with breast cancer SSI. Multivariate analysis confirms ‘surgeon department’, ‘home with surgical drains’ and ‘post-operative seroma’ to be predictive of SSI. Implications: The findings reinforced the indispensable role of interprofessional efforts in SSI prevention, to improve the outcome of predictive variables for wound infection. Moreover, healthcare professionals would be better able to identify high risk patients based on the identified independent variables. To improve the validity and applicability of the results, future researchers can perform a cross-institutional record review of post-operative breast cancer patients in Singapore.
URI: https://scholarbank.nus.edu.sg/handle/10635/153797
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