Please use this identifier to cite or link to this item: https://doi.org/10.3390/nu10091272
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dc.titleDietary cholesterol contained in whole eggs is not well absorbed and does not acutely affect plasma total cholesterol concentration in men and women: Results from 2 randomized controlled crossover studies
dc.contributor.authorKim J.E.
dc.contributor.authorCampbell W.W.
dc.date.accessioned2019-03-06T05:05:31Z
dc.date.available2019-03-06T05:05:31Z
dc.date.issued2018
dc.identifier.citationKim J.E., Campbell W.W. (2018). Dietary cholesterol contained in whole eggs is not well absorbed and does not acutely affect plasma total cholesterol concentration in men and women: Results from 2 randomized controlled crossover studies. Nutrients 10 (9) : 1272. ScholarBank@NUS Repository. https://doi.org/10.3390/nu10091272
dc.identifier.issn20726643
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/152022
dc.description.abstractWhole egg is a food source of dietary cholesterol and inconsistent research findings exist about the effect of dietary cholesterol from whole egg on blood cholesterol concentration. We assessed the effect of co-consuming cooked whole egg (CWE) on dietary cholesterol absorption from two randomized-crossover studies. For study 1, 16 men consumed raw vegetables with no egg, 75 g CWE, or 150 g CWE. For study 2, 17 women consumed cooked vegetables with no egg or 100 g CWE. Triacylglycerol-rich lipoprotein fractions (TRL) were isolated from collected blood. In study 1, total-cholesterol areas under the curve (AUC)0�h in TRL were not different but triacylglycerol AUC0�h in TRL was greater for 150 g CWE vs. 75 g CWE and no egg. Similarly, in study 2, total-cholesterol AUC0�h in TRL was not different but triacylglycerol AUC0�h in TRL was greater for 100 g CWE vs. no egg. In both studies, whole egg consumption did not affect plasma total-cholesterol AUC0�h, while triacylglycerol AUC0�h was increased. These results suggest that the dietary cholesterol in whole egg was not well absorbed, which may provide mechanistic insight for why it does not acutely influence plasma total-cholesterol concentration and is not associated with longer-term plasma cholesterol control. � 2018 by the authors. Licensee MDPI, Basel, Switzerland.
dc.publisherMDPI AG
dc.sourceScopus
dc.subjectDietary cholesterol
dc.subjectTotal cholesterol
dc.subjectTriacylglycerol
dc.subjectTriacylglycerol-rich lipoprotein fractions
dc.subjectWhole egg
dc.typeArticle
dc.contributor.departmentDEPT OF CHEMISTRY
dc.description.doi10.3390/nu10091272
dc.description.sourcetitleNutrients
dc.description.volume10
dc.description.issue9
dc.description.page1272
dc.grant.idR-143-000-A03-133
dc.grant.fundingagencyNUS, National University of Singapore
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