Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/151883
Title: TOWARDS COST-EFFECTIVENESS ANALYSIS OF SEASONAL INFLUENZA TO SUPPORT GLOBAL HEALTH ALLOCATIONS
Authors: WANG CHENGNA
Keywords: cost-effectiveness, seasonal influenza, QALY, priority setting, meta-analysis,systematic review
Issue Date: 24-Aug-2017
Citation: WANG CHENGNA (2017-08-24). TOWARDS COST-EFFECTIVENESS ANALYSIS OF SEASONAL INFLUENZA TO SUPPORT GLOBAL HEALTH ALLOCATIONS. ScholarBank@NUS Repository.
Abstract: This thesis examined key issues to evaluate modelling approaches to increase the transferability of cost-effectiveness analyses towards LMICs, with views to increase global capacity to allocate health interventions. I used seasonal influenza as a cases study to illustrate the models. The first approach is mechanism model. The main findings show that immunization of school children is likely to be cost-effective in HICs and also cost-effective in middle-income countries. The second approach is phenomenological model. The meta-analyses highlighted the importance of the unit price of the intervention, the perspective of the study and the timing of vaccination on cost-effectiveness ratios (CERs) for seasonal influenza interventions. In conclusion, these two model approaches, to some extent, both provide possibility to increase the transferability of CEAs towards LMICs and also provide some policy implications like seasonal influenza vaccination might be cost-effective in some middle-income countries.
URI: http://scholarbank.nus.edu.sg/handle/10635/151883
Appears in Collections:Ph.D Theses (Open)

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