Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/151858
Title: A PROSPECTIVE STUDY ON DIET, DISEASE AND LIFESTYLE FACTORS ASSOCIATED WITH RISK OF ACTIVE TUBERCULOSIS AMONG MIDDLE-AGED AND ELDERLY CHINESE IN SINGAPORE
Authors: SOH ZIXIN, AVRIL
Keywords: Epidemiology, Tuberculosis, Cohort study
Issue Date: 28-Sep-2018
Citation: SOH ZIXIN, AVRIL (2018-09-28). A PROSPECTIVE STUDY ON DIET, DISEASE AND LIFESTYLE FACTORS ASSOCIATED WITH RISK OF ACTIVE TUBERCULOSIS AMONG MIDDLE-AGED AND ELDERLY CHINESE IN SINGAPORE. ScholarBank@NUS Repository.
Abstract: Tuberculosis (TB) is the leading cause of death worldwide from an infectious disease. Only approximately 10% of infected individuals develop active TB, suggesting other factors that affect active disease development. Smoking, alcohol, diabetes, and low body mass index have been identified as TB risk factors, but the effect of joint exposures remains unclear. Dietary components such as tea, lipids and vitamins may also modulate TB risk, but the evidence were mainly from experimental models or retrospective case-control studies, which either lack applicability to human populations or are subject to reverse causality. The examination of host factors in relation to TB disease can contribute to deeper understanding of disease etiology and supports the development of more effective TB control strategies in the population. In this thesis, we investigated the independent and joint effect of lifestyle and dietary factors in relation to risk of active TB in a prospective cohort in Singapore.
URI: http://scholarbank.nus.edu.sg/handle/10635/151858
Appears in Collections:Ph.D Theses (Open)

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