Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/149785
Title: LONGITUDINAL PATTERNS OF GLYCEMIC CONTROL AMONG PATIENTS WITH DIABETES
Authors: LUO MIYANG
Keywords: diabetes, glycemic control, HbA1c, latent class growth analysis, disease management, epidemiology
Issue Date: 14-Aug-2018
Citation: LUO MIYANG (2018-08-14). LONGITUDINAL PATTERNS OF GLYCEMIC CONTROL AMONG PATIENTS WITH DIABETES. ScholarBank@NUS Repository.
Abstract: Glycemic control is the primary strategy to improve diabetes-related outcomes in patients with diabetes. In clinical practice, glycated hemoglobin (HbA1c) is routinely measured to evaluate level of glycemic control. These serial measurements of HbA1c form a trajectory of glycemic control, reflecting the progression of diabetes for each patient. This thesis analyzed longitudinal HbA1c patterns among patients with diabetes using data from the Singapore Population Health Studies-Diabetic Cohort. The following aspects were analyzed: (1) identifying distinct glycemic control patterns using latent class growth analysis; (2) examining the associations of these patterns with patient characteristics, control of cardiovascular biomarkers, and future risk of diabetes-related complications and all-cause mortality; (3) analyzing the influence of antidiabetic medication usage on the shaping of these patterns. These findings have a bearing on the management of diabetes in clinical practice and the allocation of resources and services in the healthcare system.
URI: http://scholarbank.nus.edu.sg/handle/10635/149785
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