Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.parkreldis.2003.11.003
Title: Restless legs symptoms in thyroid disorders
Authors: Tan E.K. 
Ho S.C.
Eng P.
Loh L.M.
Koh L.
Lum S.Y.
Teoh M.L.
Yih Y.
Khoo D. 
Keywords: Hyperthyroidism
Hypothyroidism
Restless legs syndrome
Issue Date: 2004
Publisher: Elsevier BV
Citation: Tan E.K., Ho S.C., Eng P., Loh L.M., Koh L., Lum S.Y., Teoh M.L., Yih Y., Khoo D. (2004). Restless legs symptoms in thyroid disorders. Parkinsonism and Related Disorders 10 (3) : 149-151. ScholarBank@NUS Repository. https://doi.org/10.1016/j.parkreldis.2003.11.003
Abstract: Dopaminergic dysfunction is associated with thyroid disorders and restless legs syndrome (RLS). In a 'face-to-face' interview, we evaluated for RLS using the diagnostic criteria of the International Restless Legs Syndrome Study Group (IRLSSG) in patients diagnosed biochemically with either hyper- or hypothyroidism, and in controls without thyroid disorders. Amongst 146 consecutive patients with biochemically confirmed thyroid disorders, none satisfied all the IRLSSG criteria of RLS, similar to the control population (0.2%, 1/434). However, we found 8.2% (12/146) with RLS-like symptoms (satisfied the first 3 IRLSSG criteria) compared to 0.9% (4/434) in the controls (p<0.0001). Four (33.3%) of these patients reported complete resolution of these symptoms after treatment for their thyroid condition. In conclusion, while RLS-like symptoms were observed in some patients with thyroid disorders, our study demonstrates no significant difference of RLS prevalence between patients with thyroid disorders and euthyroid controls. © 2004 Elsevier Ltd. All rights reserved.
Source Title: Parkinsonism and Related Disorders
URI: http://scholarbank.nus.edu.sg/handle/10635/149660
ISSN: 13538020
DOI: 10.1016/j.parkreldis.2003.11.003
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