Please use this identifier to cite or link to this item:
|Title:||Cardiopulmonary bypass time: Every minute counts||Authors:||Madhavan S.
|Keywords:||Coronary artery bypass
|Issue Date:||24-Jul-2017||Publisher:||Edizioni Minerva Medica||Citation:||Madhavan S., Chan S.-P., Tan W.-C., Eng J., Li B., Luo H.-D., Teoh L.-K.K. (2017-07-24). Cardiopulmonary bypass time: Every minute counts. Journal of Cardiovascular Surgery 59 (2) : 274-281. ScholarBank@NUS Repository. https://doi.org/10.23736/S0021-9509.17.09864-0||Abstract:||BACKGROUND: This study was conducted to examine the impact of CPB times on postoperative outcomes. We sought to determine the optimum cut-offs of CPB per graft time and cumulative CPB time and their predictive accuracy for mortality in conjunction with EuroSCORE II. METHODS: The de-identified data of 1960 patients who had undergone isolated on-pump CABG from 2009 to 2014 were analyzed. The risk strata of cardiopulmonary bypass (CPB)/graft and cumulative CPB times, identified with a decision tree, were added into an augmented model for predicting short-And intermediate-Term postoperative clinical events. RESULTS: Prolonged cumulative CPB time (>180 minutes) was significant in predicting mortality while adjusting for EuroSCORE II, postoperative complications, prolonged ICU stay and prolonged mechanical ventilation. Whereas prolonged CPB/graft time (>56 minutes) was marginally non-significant in terms of its direct effects, its indirect effect on mortality could be manifested through enhanced risks of complications, prolonged ICU stay (>48 hours) and prolonged mechanical ventilation (>24 hours). CONCLUSIONS: Prolonged CPB times could predict postoperative clinical events, in particular mortality. To minimize the occurrence of unfavorable adverse outcomes, it is recommended that the CPB/graft time and cumulative CPB time be kept below 56 minutes and 180 minutes respectively. � 2018 Edizioni Minerva Medica.||Source Title:||Journal of Cardiovascular Surgery||URI:||http://scholarbank.nus.edu.sg/handle/10635/146724||ISSN:||00219509||DOI:||10.23736/S0021-9509.17.09864-0|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Sep 13, 2020
WEB OF SCIENCETM
checked on Jul 25, 2019
checked on Sep 18, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.