Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/145436
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dc.titleCYTOTOXICITY MEDIATED BY L-AMINO ACID OXIDASE ISOLATED FROM THE VENOM OF CROTALUS MITCHELLII PYRRHUS
dc.contributor.authorTAN KOK KEONG
dc.date.accessioned2018-07-31T18:00:50Z
dc.date.available2018-07-31T18:00:50Z
dc.date.issued2018-01-22
dc.identifier.citationTAN KOK KEONG (2018-01-22). CYTOTOXICITY MEDIATED BY L-AMINO ACID OXIDASE ISOLATED FROM THE VENOM OF CROTALUS MITCHELLII PYRRHUS. ScholarBank@NUS Repository.
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/145436
dc.description.abstractThis thesis examines the mechanism of cytotoxicity of an L-amino acid oxidase isolated from snake venom in prostate cancer cell line. The enzyme causes oxidative stress, induces ER stress and activates autophagy in the cells in vitro, leading to the activation of apoptosis.
dc.language.isoen
dc.subjectsnake venom LAAO, cytotoxicity, cancer cells, oxidative stress, apoptosis
dc.typeThesis
dc.contributor.departmentANATOMY
dc.contributor.supervisorBAY BOON HUAT
dc.contributor.supervisorGOPALAKRISHNAKONE, P
dc.contributor.supervisorHERATH JAYANTHA GUNARATNE
dc.description.degreePh.D
dc.description.degreeconferredDOCTOR OF PHILOSOPHY
Appears in Collections:Ph.D Theses (Open)

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