SYNTHESIS OF MAGNETIC NANOMATERIALS AND THEIR BIOMEDICAL APPLICATIONS

Abstract

MAGNETIC NANOMATERIALS ARE PROMISING AS MAGNETIC HYPERTHERMIA AGENTS AND MAGNETIC RESONANCE IMAGING (MRI) CONTRAST AGENTS. THEREFORE, A RESEARCH INTO THE MAGNETIC NANOMATERIALS FOR BETTER BIOMEDICAL APPLICATIONS IS ONE OF THE MOST IMPORTANT ISSUES IN MAGNETIC RESEARCH COMMUNITY. THE THESIS FOCUSES ON THE SYNTHESIS AND APPLICATION OF MAGNETIC NANOMATERIALS AS MAGNETIC HYPERTHERMIA HEATING SEEDS AND MRI CONTRAST AGENTS. OCTAHEDRAL FE3O4 MAGNETIC NANOPARTICLES WERE SYNTHESIZED FOR HIGH PERFORMANCE MAGNETIC HYPERTHERMIA AND THE RESULTS SUGGESTED THAT OCTAHEDRAL FE3O4 MAGNETIC NANOPARTICLES HAVE HIGH SAR VALUES WITH WIDE SIZE RANGE. MOREOVER, THE FE3O4 NANORODS WERE ALSO SYNTHESIZED AND THE MAGNETIC HYPERTHERMIA PROPERTIES WERE INVESTIGATED. TO ACHIEVE A BETTER PRACTICAL APPLICATION, GADOLINIUM DOPED IRON OXIDE NANOPARTICLES WERE SYNTHESIZED WITH SUITABLE HYDRODYNAMIC SIZE TO ACHIEVE A HIGH LONGITUDINAL RELAXIVITY IN MRI. FINALLY, THE IN VIVO MRI AND MAGNETIC HYPERTHERMIA PROPERTIES OF GADO