Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pgen.1004876
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dc.titleIdentification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
dc.contributor.authorMahajan A.
dc.contributor.authorSIM XUELING
dc.contributor.authorNg H.J.
dc.contributor.authorManning A.
dc.contributor.authorRivas M.A.
dc.contributor.authorHighland H.M.
dc.contributor.authorLocke A.E.
dc.contributor.authorGrarup N.
dc.contributor.authorIm H.K.
dc.contributor.authorCingolani P.
dc.contributor.authorFlannick J.
dc.contributor.authorFontanillas P.
dc.contributor.authorFuchsberger C.
dc.contributor.authorGaulton K.J.
dc.contributor.authorTeslovich T.M.
dc.contributor.authorRayner N.W.
dc.contributor.authorRobertson N.R.
dc.contributor.authorBeer N.L.
dc.contributor.authorRundle J.K.
dc.contributor.authorBork-Jensen J.
dc.contributor.authorLadenvall C.
dc.contributor.authorBlancher C.
dc.contributor.authorBuck D.
dc.contributor.authorBuck G.
dc.contributor.authorBurtt N.P.
dc.contributor.authorGabriel S.
dc.contributor.authorGjesing A.P.
dc.contributor.authorGroves C.J.
dc.contributor.authorHollensted M.
dc.contributor.authorHuyghe J.R.
dc.contributor.authorJackson A.U.
dc.contributor.authorJun G.
dc.contributor.authorJustesen J.M.
dc.contributor.authorMangino M.
dc.contributor.authorMurphy J.
dc.contributor.authorNeville M.
dc.contributor.authorOnofrio R.
dc.contributor.authorSmall K.S.
dc.contributor.authorStringham H.M.
dc.contributor.authorSyvänen A.-C.
dc.contributor.authorTrakalo J.
dc.contributor.authorAbecasis G.
dc.contributor.authorBell G.I.
dc.contributor.authorBlangero J.
dc.contributor.authorCox N.J.
dc.contributor.authorDuggirala R.
dc.contributor.authorHanis C.L.
dc.contributor.authorSeielstad M.
dc.contributor.authorWilson J.G.
dc.contributor.authorChristensen C.
dc.contributor.authorBrandslund I.
dc.contributor.authorRauramaa R.
dc.contributor.authorSurdulescu G.L.
dc.contributor.authorDoney A.S.F.
dc.contributor.authorLannfelt L.
dc.contributor.authorLinneberg A.
dc.contributor.authorIsomaa B.
dc.contributor.authorTuomi T.
dc.contributor.authorJørgensen M.E.
dc.contributor.authorJørgensen T.
dc.contributor.authorKuusisto J.
dc.contributor.authorUusitupa M.
dc.contributor.authorSalomaa V.
dc.contributor.authorSpector T.D.
dc.contributor.authorMorris A.D.
dc.contributor.authorPalmer C.N.A.
dc.contributor.authorCollins F.S.
dc.contributor.authorMohlke K.L.
dc.contributor.authorBergman R.N.
dc.contributor.authorIngelsson E.
dc.contributor.authorLind L.
dc.contributor.authorTuomilehto J.
dc.contributor.authorHansen T.
dc.contributor.authorWatanabe R.M.
dc.contributor.authorProkopenko I.
dc.contributor.authorDupuis J.
dc.contributor.authorKarpe F.
dc.contributor.authorGroop L.
dc.contributor.authorLaakso M.
dc.contributor.authorPedersen O.
dc.contributor.authorFlorez J.C.
dc.contributor.authorMorris A.P.
dc.contributor.authorAltshuler D.
dc.contributor.authorMeigs J.B.
dc.contributor.authorBoehnke M.
dc.contributor.authorMcCarthy M.I.
dc.contributor.authorLindgren C.M.
dc.contributor.authorGloyn A.L.
dc.contributor.authorAbboud H.E.
dc.contributor.authorAfzal U.
dc.contributor.authorAguilar D.
dc.contributor.authorArya R.
dc.contributor.authorAtzmon G.
dc.contributor.authorAung T.
dc.contributor.authorBanks E.
dc.contributor.authorBarroso I.
dc.contributor.authorBarzilai N.
dc.contributor.authorBelow J.E.
dc.contributor.authorBharadwaj D.
dc.contributor.authorBlackwell T.W.
dc.contributor.authorBonnycastle L.L.
dc.contributor.authorBowden D.
dc.contributor.authorCarey J.
dc.contributor.authorCarneiro M.O.
dc.contributor.authorChambers J.C.
dc.contributor.authorChan E.
dc.contributor.authorChan J.
dc.contributor.authorChandak G.R.
dc.contributor.authorChen P.
dc.contributor.authorChen Y.
dc.contributor.authorChen H.
dc.contributor.authorCheng C.-Y.
dc.contributor.authorChia K.S.
dc.contributor.authorCho Y.S.
dc.contributor.authorCorrea A.
dc.contributor.authorCurran J.E.
dc.contributor.authorDaly M.J.
dc.contributor.authorDay-Williams A.G.
dc.contributor.authorDeFronzo R.A.
dc.contributor.authorDePristo M.
dc.contributor.authorDonnelly P.J.
dc.contributor.authorEbrahim S.B.
dc.contributor.authorElliott P.
dc.contributor.authorEsko T.
dc.contributor.authorFadista J.
dc.contributor.authorFarjoun Y.
dc.contributor.authorFarmer A.J.
dc.contributor.authorFarook V.S.
dc.contributor.authorFennell T.
dc.contributor.authorFerreira T.
dc.contributor.authorFingerlin T.
dc.contributor.authorForsén T.
dc.contributor.authorFowler S.P.
dc.contributor.authorFranks P.W.
dc.contributor.authorFrayling T.M.
dc.contributor.authorFreedman B.I.
dc.contributor.authorFroguel P.
dc.contributor.authorGamazon E.R.
dc.contributor.authorGieger C.
dc.contributor.authorGlaser B.
dc.contributor.authorGo M.J.
dc.contributor.authorGoldstein J.I.
dc.contributor.authorGrallert H.
dc.contributor.authorGrant G.
dc.contributor.authorGreen T.
dc.contributor.authorGriswold M.
dc.contributor.authorHale D.E.
dc.contributor.authorHan B.-G.
dc.contributor.authorHartl C.
dc.contributor.authorHattersley A.T.
dc.contributor.authorHicks P.J.
dc.contributor.authorHodgkiss D.
dc.contributor.authorHorikoshi M.
dc.contributor.authorHrabé de Angelis M.
dc.contributor.authorHu C.
dc.contributor.authorHu F.B.
dc.contributor.authorHuh I.
dc.contributor.authorKamran Ikram M.
dc.contributor.authorIllig T.
dc.contributor.authorJablonski K.A.
dc.contributor.authorJenkinson C.P.
dc.contributor.authorJia W.
dc.contributor.authorKang H.M.
dc.contributor.authorKhor C.-C.
dc.contributor.authorKim Y.
dc.contributor.authorKim Y.J.
dc.contributor.authorKim B.-J.
dc.contributor.authorKinnunen L.
dc.contributor.authorKooner J.S.
dc.contributor.authorKravic J.
dc.contributor.authorKriebel J.
dc.contributor.authorKumar A.
dc.contributor.authorKumar S.
dc.contributor.authorKuulasmaa T.
dc.contributor.authorKwon M.-S.
dc.contributor.authorLangenberg C.
dc.contributor.authorLauritzen T.
dc.contributor.authorLee S.
dc.contributor.authorLee J.
dc.contributor.authorLee J.
dc.contributor.authorLee J.-Y.
dc.contributor.authorLehman D.M.
dc.contributor.authorLehne B.
dc.contributor.authorLevy J.C.
dc.contributor.authorLi J.
dc.contributor.authorLiang L.
dc.contributor.authorLim W.Y.
dc.contributor.authorLin K.-H.
dc.contributor.authorLiu J.
dc.contributor.authorLoh M.
dc.contributor.authorMa R.C.W.
dc.contributor.authorMa C.
dc.contributor.authorMägi R.
dc.contributor.authorMaguire J.
dc.contributor.authorMaxwell T.J.
dc.contributor.authorMcVean G.
dc.contributor.authorMeisinger C.
dc.contributor.authorMeitinger T.
dc.contributor.authorMelander O.
dc.contributor.authorMetspalu A.
dc.contributor.authorMihailov E.
dc.contributor.authorMilani L.
dc.contributor.authorMoutsianas L.
dc.contributor.authorMüller-Nurasyid M.
dc.contributor.authorK. Musani S.
dc.contributor.authorNagai Y.
dc.contributor.authorNarisu N.
dc.contributor.authorNeale B.M.
dc.contributor.authorNg M.C.Y.
dc.contributor.authorNilsson P.
dc.contributor.authorO'Rahilly S.P.
dc.contributor.authorOrho-Melander M.
dc.contributor.authorOwen K.R.
dc.contributor.authorPalmer N.D.
dc.contributor.authorPark T.
dc.contributor.authorPasko D.
dc.contributor.authorPearson R.D.
dc.contributor.authorPerry J.R.B.
dc.contributor.authorPeters A.
dc.contributor.authorPollin T.I.
dc.contributor.authorPoplin R.
dc.contributor.authorPrabhakaran D.
dc.contributor.authorPuppala S.
dc.contributor.authorPurcell S.
dc.contributor.authorQi L.
dc.contributor.authorQi Q.
dc.contributor.authorRoden M.
dc.contributor.authorRolandsson O.
dc.contributor.authorRosengren A.H.
dc.contributor.authorSandhu M.
dc.contributor.authorSchwarzmayr T.
dc.contributor.authorScott L.J.
dc.contributor.authorScott R.A.
dc.contributor.authorScott J.
dc.contributor.authorScott W.R.
dc.contributor.authorSehmi J.
dc.contributor.authorShakir K.
dc.contributor.authorSladek R.
dc.contributor.authorSmith J.D.
dc.contributor.authorStancáková A.
dc.contributor.authorStrauch K.
dc.contributor.authorStrom T.M.
dc.contributor.authorSwift A.
dc.contributor.authorTai E.S.
dc.contributor.authorTajes J.F.
dc.contributor.authorTan S.-T.
dc.contributor.authorTandon N.
dc.contributor.authorTaylor H.A.
dc.contributor.authorJr.
dc.contributor.authorTeo Y.Y.
dc.contributor.authorThameem F.
dc.contributor.authorThorand B.
dc.contributor.authorvan de Bunt M.
dc.contributor.authorVarga T.V.
dc.contributor.authorWalker M.
dc.contributor.authorWareham N.J.
dc.contributor.authorWelch R.P.
dc.contributor.authorWieland T.
dc.contributor.authorWilson G.
dc.contributor.authorSr.
dc.contributor.authorWong T.Y.
dc.contributor.authorWood A.R.
dc.contributor.authorYoon J.
dc.contributor.authorZeggini E.
dc.contributor.authorZhang W.
dc.date.accessioned2018-05-23T07:03:00Z
dc.date.available2018-05-23T07:03:00Z
dc.date.issued2015
dc.identifier.citationMahajan A., SIM XUELING, Ng H.J., Manning A., Rivas M.A., Highland H.M., Locke A.E., Grarup N., Im H.K., Cingolani P., Flannick J., Fontanillas P., Fuchsberger C., Gaulton K.J., Teslovich T.M., Rayner N.W., Robertson N.R., Beer N.L., Rundle J.K., Bork-Jensen J., Ladenvall C., Blancher C., Buck D., Buck G., Burtt N.P., Gabriel S., Gjesing A.P., Groves C.J., Hollensted M., Huyghe J.R., Jackson A.U., Jun G., Justesen J.M., Mangino M., Murphy J., Neville M., Onofrio R., Small K.S., Stringham H.M., Syvänen A.-C., Trakalo J., Abecasis G., Bell G.I., Blangero J., Cox N.J., Duggirala R., Hanis C.L., Seielstad M., Wilson J.G., Christensen C., Brandslund I., Rauramaa R., Surdulescu G.L., Doney A.S.F., Lannfelt L., Linneberg A., Isomaa B., Tuomi T., Jørgensen M.E., Jørgensen T., Kuusisto J., Uusitupa M., Salomaa V., Spector T.D., Morris A.D., Palmer C.N.A., Collins F.S., Mohlke K.L., Bergman R.N., Ingelsson E., Lind L., Tuomilehto J., Hansen T., Watanabe R.M., Prokopenko I., Dupuis J., Karpe F., Groop L., Laakso M., Pedersen O., Florez J.C., Morris A.P., Altshuler D., Meigs J.B., Boehnke M., McCarthy M.I., Lindgren C.M., Gloyn A.L., Abboud H.E., Afzal U., Aguilar D., Arya R., Atzmon G., Aung T., Banks E., Barroso I., Barzilai N., Below J.E., Bharadwaj D., Blackwell T.W., Bonnycastle L.L., Bowden D., Carey J., Carneiro M.O., Chambers J.C., Chan E., Chan J., Chandak G.R., Chen P., Chen Y., Chen H., Cheng C.-Y., Chia K.S., Cho Y.S., Correa A., Curran J.E., Daly M.J., Day-Williams A.G., DeFronzo R.A., DePristo M., Donnelly P.J., Ebrahim S.B., Elliott P., Esko T., Fadista J., Farjoun Y., Farmer A.J., Farook V.S., Fennell T., Ferreira T., Fingerlin T., Forsén T., Fowler S.P., Franks P.W., Frayling T.M., Freedman B.I., Froguel P., Gamazon E.R., Gieger C., Glaser B., Go M.J., Goldstein J.I., Grallert H., Grant G., Green T., Griswold M., Hale D.E., Han B.-G., Hartl C., Hattersley A.T., Hicks P.J., Hodgkiss D., Horikoshi M., Hrabé de Angelis M., Hu C., Hu F.B., Huh I., Kamran Ikram M., Illig T., Jablonski K.A., Jenkinson C.P., Jia W., Kang H.M., Khor C.-C., Kim Y., Kim Y.J., Kim B.-J., Kinnunen L., Kooner J.S., Kravic J., Kriebel J., Kumar A., Kumar S., Kuulasmaa T., Kwon M.-S., Langenberg C., Lauritzen T., Lee S., Lee J., Lee J., Lee J.-Y., Lehman D.M., Lehne B., Levy J.C., Li J., Liang L., Lim W.Y., Lin K.-H., Liu J., Loh M., Ma R.C.W., Ma C., Mägi R., Maguire J., Maxwell T.J., McVean G., Meisinger C., Meitinger T., Melander O., Metspalu A., Mihailov E., Milani L., Moutsianas L., Müller-Nurasyid M., K. Musani S., Nagai Y., Narisu N., Neale B.M., Ng M.C.Y., Nilsson P., O'Rahilly S.P., Orho-Melander M., Owen K.R., Palmer N.D., Park T., Pasko D., Pearson R.D., Perry J.R.B., Peters A., Pollin T.I., Poplin R., Prabhakaran D., Puppala S., Purcell S., Qi L., Qi Q., Roden M., Rolandsson O., Rosengren A.H., Sandhu M., Schwarzmayr T., Scott L.J., Scott R.A., Scott J., Scott W.R., Sehmi J., Shakir K., Sladek R., Smith J.D., Stancáková A., Strauch K., Strom T.M., Swift A., Tai E.S., Tajes J.F., Tan S.-T., Tandon N., Taylor H.A., Jr., Teo Y.Y., Thameem F., Thorand B., van de Bunt M., Varga T.V., Walker M., Wareham N.J., Welch R.P., Wieland T., Wilson G., Sr., Wong T.Y., Wood A.R., Yoon J., Zeggini E., Zhang W. (2015). Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus. PLoS ONE 11 (1) : e1004876. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pgen.1004876
dc.identifier.issn15537390
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/142266
dc.publisherPublic Library of Science (PloS)
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentDEPT OF BIOCHEMISTRY
dc.contributor.departmentDEPT OF MEDICINE
dc.contributor.departmentDEPT OF OPHTHALMOLOGY
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.contributor.departmentSAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
dc.description.doi10.1371/journal.pgen.1004876
dc.description.sourcetitlePLoS ONE
dc.description.volume11
dc.description.issue1
dc.description.pagee1004876
dc.identifier.isiut000349314600012
dc.published.statePublished
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