Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/139080
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dc.titleA STUDY ON COMPACTION PUNCH DESIGN ON TABLET PROPERTIES
dc.contributor.authorPARTHIBAN S/O ANBALAGAN
dc.date.accessioned2018-02-28T18:00:47Z
dc.date.available2018-02-28T18:00:47Z
dc.date.issued2017-08-22
dc.identifier.citationPARTHIBAN S/O ANBALAGAN (2017-08-22). A STUDY ON COMPACTION PUNCH DESIGN ON TABLET PROPERTIES. ScholarBank@NUS Repository.
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/139080
dc.description.abstractTablet compaction punches have undergone many changes to their design specifications over the years in an effort to improve manufacturing efficiency, tablet quality and durability of the tools. This study was initiated with the objective of understanding the impact of developing new punch designs on tablet physical quality. In the first part of the work, the influence of different deformation mechanisms of tableting materials during the dwell phase and the consequent effect on tablet mechanical properties was investigated. In the subsequent parts of the study, the influence of punch head and face modification on the tableting process and tableting performance under different compaction conditions was determined. This research study provided a comprehensive understanding on the advantages and limitations of punch head and face configurational changes with respect to tablet properties. The findings may aid tablet press and tools manufacturers in process and tool design considerations for a successful tableting program.
dc.language.isoen
dc.subjectPowder compaction, Particle deformation, Punch head, Punch face, Tablet capping, Powder sticking
dc.typeThesis
dc.contributor.departmentPHARMACY
dc.contributor.supervisorLIEW, CELINE VALERIA
dc.contributor.supervisorHENG WAN SIA, PAUL
dc.description.degreePh.D
dc.description.degreeconferredDOCTOR OF PHILOSOPHY
Appears in Collections:Ph.D Theses (Open)

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