Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/134327
DC Field | Value | |
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dc.title | Vasoactive intestinal peptide secreting tumours in children: a case report with literature review. | |
dc.contributor.author | Quak, S.H. | |
dc.contributor.author | Prabhakaran, K. | |
dc.contributor.author | Kwok, R. | |
dc.contributor.author | O'Reilly, A.P. | |
dc.date.accessioned | 2016-12-20T08:45:58Z | |
dc.date.available | 2016-12-20T08:45:58Z | |
dc.date.issued | 1988-02 | |
dc.identifier.citation | Quak, S.H., Prabhakaran, K., Kwok, R., O'Reilly, A.P. (1988-02). Vasoactive intestinal peptide secreting tumours in children: a case report with literature review.. Australian Paediatric Journal 24 (1) : 55-58. ScholarBank@NUS Repository. | |
dc.identifier.issn | 0004993X | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/134327 | |
dc.description.abstract | A 3 year old Chinese girl with watery diarrhoea, abdominal distension and hypokalaemia due to a thoracic paraspinal vasoactive intestinal peptide (VIP) secreting ganglioneuroma is reported. The pre-operative serum VIP was 314 pmol/l (normal less than 30). Her diarrhoea stopped after the removal of the tumour. The VIP was 14 pmol/l 6 months post-operatively. Review of the 19 reported cases in children with documented elevated serum VIP showed that many of the cases presented with watery diarrhoea for prolonged duration before the diagnosis was made. Earliest age of onset was 2 weeks of age. The male to female ratio was 9:10. Ganglioneuroma and ganglioneuroblastoma were the commonest tumours. Pancreatic non-beta cell hyperplasia and neurofibroma were also reported. Location of the tumour was variable: neck, chest or abdomen. Increased urinary catecholamine excretion was reported in 50% of the cases. Abdominal distension, flushing, episodic hypertension and failure to thrive were the other associated features. | |
dc.type | Review | |
dc.contributor.department | PAEDIATRICS | |
dc.description.sourcetitle | Australian Paediatric Journal | |
dc.description.volume | 24 | |
dc.description.issue | 1 | |
dc.description.page | 55-58 | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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