Please use this identifier to cite or link to this item:
|Title:||Specific 3H-cimetidine binding to receptors in the submandibular gland of the rat||Authors:||Sim, M.K.
|Issue Date:||1985||Citation:||Sim, M.K., Ang, S.B. (1985). Specific 3H-cimetidine binding to receptors in the submandibular gland of the rat. Japanese Journal of Pharmacology 37 (2) : 203-206. ScholarBank@NUS Repository.||Abstract:||Recent studies indicate that the secretagogue action of histamine on the salivary gland is mediated via H2-receptors. In this study we attempt to characterize the histamine H2-receptors in the submandibular gland of the rat. The results show the presence of a specific 3H-cimetidine binding site in the gland. However, the binding constants of this site are not fully characteristic of the specific 3H-cimetidine-H2-receptor binding. They tend to indicate that the binding of 3H-cimetidine to the gland membrane is similar to the well-characterized 3H-cimetidine-imidazole-recognition-receptor binding found in the membrane of the brain, gastric mucosae and atrium of various mammalian species.||Source Title:||Japanese Journal of Pharmacology||URI:||http://scholarbank.nus.edu.sg/handle/10635/134283||ISSN:||00215198|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.