Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/134000
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dc.titlePulmonary edema as a cause for fulminant death following microinjection of kainic acid into the rat medulla oblongata
dc.contributor.authorChan, S.H.H.
dc.contributor.authorChong, A.P.Y.
dc.contributor.authorOng, B.T.
dc.contributor.authorChong, O.K.
dc.contributor.authorLim, H.C.
dc.date.accessioned2016-12-20T08:42:23Z
dc.date.available2016-12-20T08:42:23Z
dc.date.issued1985-12-18
dc.identifier.citationChan, S.H.H., Chong, A.P.Y., Ong, B.T., Chong, O.K., Lim, H.C. (1985-12-18). Pulmonary edema as a cause for fulminant death following microinjection of kainic acid into the rat medulla oblongata. Neuroscience Letters 62 (3) : 341-346. ScholarBank@NUS Repository.
dc.identifier.issn03043940
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/134000
dc.description.abstractThe present study confirmed histopathologically the suggestion that pulmonary edema may underlie the fulminant death following microinjection of kainic acid into many medullary sites in rats anesthetized with pentobarbital sodium. We also observed a sustained elevation in systemic arterial pressure, cardiac contractility and heart rate before the animal succumbed to kainate neurotoxicity. It is suggested that the increased systemic hydrostatic pressure may retrogradely promote pulmonary hypertension that precipitates pulmonary edema. © 1985.
dc.subjectfulminant death
dc.subjectkainic acid
dc.subjectmedulla oblongata rat
dc.subjectneurotoxicity
dc.subjectpulmonary edema
dc.typeArticle
dc.contributor.departmentPHYSIOLOGY
dc.description.sourcetitleNeuroscience Letters
dc.description.volume62
dc.description.issue3
dc.description.page341-346
dc.description.codenNELED
dc.identifier.isiutNOT_IN_WOS
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