Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/13387
DC FieldValue
dc.titleA study on roller compaction of powders
dc.contributor.authorCHEE SZE NAM
dc.date.accessioned2010-04-08T10:32:34Z
dc.date.available2010-04-08T10:32:34Z
dc.date.issued2007-09-17
dc.identifier.citationCHEE SZE NAM (2007-09-17). A study on roller compaction of powders. ScholarBank@NUS Repository.
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/13387
dc.description.abstractRoller compaction is a dry granulation process where powder is densified between two counter-rotating rollers. This study investigated the effects of material properties and processing variables on roller compaction and its product quality. As the mechanical strength of flakes was an important variable and no suitable measurement method existed, a reliable method was developed. The effects of various processing parameters and raw materials on flake formation and granules produced were studied. Roller speed exerted a greater influence than screw speed on roller compaction. Compaction force had only limited influence while dwell time did not affect flake properties. The extent of influence on compaction by the processing parameters was dependent on powder flowability. The particle size and size distribution of raw materials showed differing effects, depending on its nature. Molecular weight and chemical composition of the binder added affected product quality.
dc.language.isoen
dc.subjectRoller Compaction, Cone Penetration Breaking Strength, Material Properties, Processing Parameters, Lactose, Herb
dc.typeThesis
dc.contributor.departmentPHARMACY
dc.contributor.supervisorHENG WAN SIA, PAUL
dc.contributor.supervisorCHAN LAI WAH
dc.description.degreePh.D
dc.description.degreeconferredDOCTOR OF PHILOSOPHY
dc.identifier.isiutNOT_IN_WOS
Appears in Collections:Ph.D Theses (Open)

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
01Title_page.pdf13.57 kBAdobe PDF

OPEN

NoneView/Download
02Acknowledgements.pdf13.93 kBAdobe PDF

OPEN

NoneView/Download
03Table of Contents.pdf121.88 kBAdobe PDF

OPEN

NoneView/Download
04Summary.pdf16.18 kBAdobe PDF

OPEN

NoneView/Download
05List of Tables.pdf32.89 kBAdobe PDF

OPEN

NoneView/Download
06List of Figures.pdf65.68 kBAdobe PDF

OPEN

NoneView/Download
07List of Abbreviations-Symbols.pdf67.42 kBAdobe PDF

OPEN

NoneView/Download
08Introduction.pdf229.45 kBAdobe PDF

OPEN

NoneView/Download
09Hypotheses and Objectives.pdf15.38 kBAdobe PDF

OPEN

NoneView/Download
10Experimental.pdf266.14 kBAdobe PDF

OPEN

NoneView/Download
11Results and Discussion.pdf1.76 MBAdobe PDF

OPEN

NoneView/Download
12Conclusions.pdf18.4 kBAdobe PDF

OPEN

NoneView/Download
13References.pdf135.81 kBAdobe PDF

OPEN

NoneView/Download
14Publications.pdf15.58 kBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.