The fate and migratory patterns of the infective larvae of Brugia malayi, Dirofilaria immitis and Breinlia sergenti in Aedes togoi denied access to a host

Abstract

The developing larvae of Brugia malayi, Breinlia sergenti and Dirofilaria immitis occur in the muscle, the fat body and the malpighian tubules of mosquitoes, respectively. The fate and migratory patterns of their ineffective larvae were investigated in Aedes togoi maintained only on honey and water and denied the opportunity of a post infecting blood meal. The migratory patterns of these 3 filariae were fairly similar. There was a rapid increase of infective larvae in the head proboscis region during the first 2 to 4 days after the incubation period and a marked sponteneous escape of infective larvae from the mosquitoes during this period. There were no significant differences in the migratory pattern of ineffective larvae of B. sergenti in A. togoi fed on slow lorises with either moderate or high microfilaremia.