Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/133541
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dc.titleUltrastructure of the skeletal muscles in acromegaly. Before and after hypophysectomy
dc.contributor.authorCheah, J.S.
dc.contributor.authorChua, S.P.
dc.contributor.authorHo, C.L.
dc.date.accessioned2016-12-20T08:37:15Z
dc.date.available2016-12-20T08:37:15Z
dc.date.issued1975
dc.identifier.citationCheah, J.S., Chua, S.P., Ho, C.L. (1975). Ultrastructure of the skeletal muscles in acromegaly. Before and after hypophysectomy. American Journal of the Medical Sciences 269 (2) : 183-187. ScholarBank@NUS Repository.
dc.identifier.issn00029629
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/133541
dc.description.abstractElectron microscopic examination of the skeletal muscles in a patient with acromegaly and marked elevation of the serum growth hormone reveals altered mitochondria (pleomorphism, elongation, matrical pallor, and cristae abnormalities), glycogen granules infiltration, inclusion bodies, and vesicular dilatations. Nine months after surgical removal of the pituitary tumor, the serum growth hormone levels were markedly diminished. A repeat examination of the skeletal muscle shows that the previous ultrastructural changes were markedly diminished. It thus appears that these ultrastructural changes in the muscles are related to the growth hormone levels.
dc.typeArticle
dc.contributor.departmentMEDICINE
dc.description.sourcetitleAmerican Journal of the Medical Sciences
dc.description.volume269
dc.description.issue2
dc.description.page183-187
dc.description.codenAJMSA
dc.identifier.isiutNOT_IN_WOS
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