Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/133292
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dc.titleHepatitis B antigen in the liver cells in cirrhosis and hepatocellular carcinoma
dc.contributor.authorTan, A.Y.O.
dc.contributor.authorLaw, C.H.
dc.contributor.authorLee, Y.S.
dc.date.accessioned2016-12-19T06:49:10Z
dc.date.available2016-12-19T06:49:10Z
dc.date.issued1977
dc.identifier.citationTan, A.Y.O., Law, C.H., Lee, Y.S. (1977). Hepatitis B antigen in the liver cells in cirrhosis and hepatocellular carcinoma. Pathology 9 (1) : 57-64. ScholarBank@NUS Repository.
dc.identifier.issn00313025
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/133292
dc.description.abstractThe demonstration of hepatitis B antigen in the liver cells in formalin fixed paraffin embedded tissues by Shikata's orcein staining method affords an opportunity to conduct retrospective studies on necropsy materials. Such a study in Singapore showed orcein positive liver cells in 22 out of 52 (42.3%) and 37 out of 50 (74.0%) cases of cirrhosis of the liver and hepatocellular carcinoma respectively, while only 5 out of 113 (4.4%) 'normal' livers gave positive results. There is a significant difference in the frequency of hepatocellular carcinoma in orcein positive and orcein negative cirrhotic livers (28 out of 50, and 10 out of 40 respectively). These results suggest a possible etiologic relation between hepatitis B antigen and hepatocellular carcinoma.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentPATHOLOGY
dc.description.sourcetitlePathology
dc.description.volume9
dc.description.issue1
dc.description.page57-64
dc.description.codenPTLGA
dc.identifier.isiutNOT_IN_WOS
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