Please use this identifier to cite or link to this item:
Title: Hepatitis B antigen in the liver cells in cirrhosis and hepatocellular carcinoma
Authors: Tan, A.Y.O. 
Law, C.H.
Lee, Y.S. 
Issue Date: 1977
Citation: Tan, A.Y.O., Law, C.H., Lee, Y.S. (1977). Hepatitis B antigen in the liver cells in cirrhosis and hepatocellular carcinoma. Pathology 9 (1) : 57-64. ScholarBank@NUS Repository.
Abstract: The demonstration of hepatitis B antigen in the liver cells in formalin fixed paraffin embedded tissues by Shikata's orcein staining method affords an opportunity to conduct retrospective studies on necropsy materials. Such a study in Singapore showed orcein positive liver cells in 22 out of 52 (42.3%) and 37 out of 50 (74.0%) cases of cirrhosis of the liver and hepatocellular carcinoma respectively, while only 5 out of 113 (4.4%) 'normal' livers gave positive results. There is a significant difference in the frequency of hepatocellular carcinoma in orcein positive and orcein negative cirrhotic livers (28 out of 50, and 10 out of 40 respectively). These results suggest a possible etiologic relation between hepatitis B antigen and hepatocellular carcinoma.
Source Title: Pathology
ISSN: 00313025
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

checked on Apr 19, 2019

Google ScholarTM


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.