Please use this identifier to cite or link to this item: https://doi.org/10.1001/archopht.122.3.353
Title: Predilection of the Macular Region to High Incidence of Choroidal Neovascularization after Intense Laser Photocoagulation in the Monkey
Authors: Shen, W.-Y.
Lee, S.Y.
Yeo, I.
Lai, C.-M.
Mathur, R.
Tan, D. 
Constable, I.J.
Rakoczy, P.E.
Issue Date: Mar-2004
Citation: Shen, W.-Y., Lee, S.Y., Yeo, I., Lai, C.-M., Mathur, R., Tan, D., Constable, I.J., Rakoczy, P.E. (2004-03). Predilection of the Macular Region to High Incidence of Choroidal Neovascularization after Intense Laser Photocoagulation in the Monkey. Archives of Ophthalmology 122 (3) : 353-360. ScholarBank@NUS Repository. https://doi.org/10.1001/archopht.122.3.353
Abstract: Objective: To determine the key factors for creating a high incidence model of choroidal neovascularization (CNV) in the monkey. Methods: Intense laser photocoagulation was performed in 8 eyes of 4 monkeys using krypton red and green-yellow and Alcon frequency-doubled diode ophthalmic lasers Eight to 13 lesions were delivered to an area between the temporal vascular arcades in each eye Development of CNV was monitored by fluorescein angiography at 2 and 4 weeks after laser treatment, and the results were correlated with histological analysis. Results: A much higher incidence of CNV occurred in the macular region, which refers to an anatomic area equivalent to a mean ± SD 2 5 ± 0 4 times the horizontal diameter of the optic disc in the fundus Regardless of the type of ophthalmic laser used, 72% of lesions developed fluorescein leakage within the macula, compared with 12% outside the macula (P
Source Title: Archives of Ophthalmology
URI: http://scholarbank.nus.edu.sg/handle/10635/133263
ISSN: 00039950
DOI: 10.1001/archopht.122.3.353
Appears in Collections:Staff Publications

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