Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/133260
DC Field | Value | |
---|---|---|
dc.title | In vitro formation of testosterone via the Δ5-pathway in the human umbilical cord | |
dc.contributor.author | Loganath, A. | |
dc.contributor.author | Gunasegaram, R. | |
dc.contributor.author | Peh, K.L. | |
dc.contributor.author | Chow, W.P. | |
dc.contributor.author | Chew, P.C.T. | |
dc.contributor.author | Shanmugaratnam, S. | |
dc.date.accessioned | 2016-12-19T06:48:48Z | |
dc.date.available | 2016-12-19T06:48:48Z | |
dc.date.issued | 1992-04 | |
dc.identifier.citation | Loganath, A., Gunasegaram, R., Peh, K.L., Chow, W.P., Chew, P.C.T., Shanmugaratnam, S. (1992-04). In vitro formation of testosterone via the Δ5-pathway in the human umbilical cord. Steroids 57 (4) : 189-192. ScholarBank@NUS Repository. | |
dc.identifier.issn | 0039128X | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/133260 | |
dc.description.abstract | Homogenates of two groups of term umbilical cord (n = 6, 37-40 weeks; n = 6, 38-40 weeks) were separately incubated with [7n-3H]pregnenolone and [1,2,6, 7-3H]dehydroepiandrosterone. Using the reverse-isotope dilution technique, [3H]dehydroepiandrosterone and [3H] testosterone formed from the respective substrates were isolated and characterized. The extent of enzymic conversions were 0.015-0.28% and 0.044-2.2%. These results provide evidence for the metabolic transformation of pregnenolone to testosterone via the Δ5-3β-hydroxy route. © 1992. | |
dc.source | Scopus | |
dc.subject | 17α-hydroxylase | |
dc.subject | 17β-hydroxy steroid oxidoreductase | |
dc.subject | 3β-hydroxy steroid dehydrogenase-5,4-ene isomerase | |
dc.subject | androgen synthesis | |
dc.subject | C-17,20-lyase | |
dc.subject | dehydroepiandrosterone | |
dc.subject | fetoplacental unit (umbilical cord) | |
dc.subject | steroids | |
dc.subject | testosterone | |
dc.subject | testosterone synthesis by umbilical cord | |
dc.subject | umbilical cord | |
dc.type | Article | |
dc.contributor.department | OBSTETRICS & GYNAECOLOGY | |
dc.contributor.department | BIOCHEMISTRY | |
dc.description.sourcetitle | Steroids | |
dc.description.volume | 57 | |
dc.description.issue | 4 | |
dc.description.page | 189-192 | |
dc.description.coden | STEDA | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
Show simple item record
Files in This Item:
There are no files associated with this item.
Google ScholarTM
Check
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.