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|Title:||Marked elevations in N-terminal brain natriuretic peptide levels in septic shock.||Authors:||Chua, G.
|Issue Date:||Aug-2004||Citation:||Chua, G., Kang-Hoe, L. (2004-08). Marked elevations in N-terminal brain natriuretic peptide levels in septic shock.. Critical care (London, England) 8 (4) : R248-250. ScholarBank@NUS Repository.||Abstract:||INTRODUCTION: N-terminal pro brain natriuretic peptide (NT-proBNP) is a cardiac biomarker that has recently shown to be of diagnostic value in a diagnosis of decompensated heart failure, acute coronary syndromes and other conditions resulting in myocardial stretch. We sought to study whether sepsis-induced myocardial dilation would result in an elevation of NT-proBNP. METHOD: Serum NT-proBNP measurements were made in six consecutive patients with septic shock within 6 hours of admission to the intensive care unit. RESULTS: Markedly elevated levels of NT-proBNP were found in all six patients. CONCLUSIONS: NT-proBNP levels can be markedly elevated in critically ill patients presenting with septic shock. An elevated NT-proBNP level in a critically ill patient is not specific for decompensated heart failure.||Source Title:||Critical care (London, England)||URI:||http://scholarbank.nus.edu.sg/handle/10635/133215||ISSN:||1466609X|
|Appears in Collections:||Staff Publications|
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