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Title: Marked elevations in N-terminal brain natriuretic peptide levels in septic shock.
Authors: Chua, G.
Kang-Hoe, L. 
Issue Date: Aug-2004
Citation: Chua, G., Kang-Hoe, L. (2004-08). Marked elevations in N-terminal brain natriuretic peptide levels in septic shock.. Critical care (London, England) 8 (4) : R248-250. ScholarBank@NUS Repository.
Abstract: INTRODUCTION: N-terminal pro brain natriuretic peptide (NT-proBNP) is a cardiac biomarker that has recently shown to be of diagnostic value in a diagnosis of decompensated heart failure, acute coronary syndromes and other conditions resulting in myocardial stretch. We sought to study whether sepsis-induced myocardial dilation would result in an elevation of NT-proBNP. METHOD: Serum NT-proBNP measurements were made in six consecutive patients with septic shock within 6 hours of admission to the intensive care unit. RESULTS: Markedly elevated levels of NT-proBNP were found in all six patients. CONCLUSIONS: NT-proBNP levels can be markedly elevated in critically ill patients presenting with septic shock. An elevated NT-proBNP level in a critically ill patient is not specific for decompensated heart failure.
Source Title: Critical care (London, England)
ISSN: 1466609X
Appears in Collections:Staff Publications

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