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Title: Management of chronic hepatitis B in challenging patient populations
Authors: Dore, G.J.
Guan, R. 
Wasim Jafri, S.M.
Sarin, S.V.
Keeffe, E.B.
Keywords: Adolescents
Alanine aminotransferase
Human immunodeficiency virus
Liver transplantation
Special populations
Issue Date: Dec-2006
Citation: Dore, G.J., Guan, R., Wasim Jafri, S.M., Sarin, S.V., Keeffe, E.B. (2006-12). Management of chronic hepatitis B in challenging patient populations. Liver International 26 (SUPPL. 2) : 38-46. ScholarBank@NUS Repository.
Abstract: Clinicians face many challenges in striving to reduce the morbidity and mortality associated with chronic hepatitis B virus (HBV) infection. Some of the most urgent issues relate to preventing or reducing the development of antiviral resistance that may arise during oral antiviral therapy. In addition, the management of special populations, including patients with normal alanine aminotransferase levels, children and adolescents, women planning pregnancy or already pregnant, patients undergoing chemotherapy or other forms of immunosuppression, patients with HBV and human immunodeficiency virus coinfection, and those undergoing liver transplantation, present further challenges. This concise review examines recent findings on the efficacy of antiviral therapy in these special patient groups. © 2006 Blackwell Munksgaard.
Source Title: Liver International
ISSN: 14783223
DOI: 10.1111/j.1478-3231.2006.01375.x
Appears in Collections:Staff Publications

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