Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ophtha.2006.01.058
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dc.titlePeripapillary Retinal Nerve Fiber Layer Thickness Variations with Myopia
dc.contributor.authorHoh, S.-T.
dc.contributor.authorLim, M.C.C.
dc.contributor.authorSeah, S.K.L.
dc.contributor.authorLim, A.T.H.
dc.contributor.authorChew, S.-J.
dc.contributor.authorFoster, P.J.
dc.contributor.authorAung, T.
dc.date.accessioned2016-12-13T05:36:57Z
dc.date.available2016-12-13T05:36:57Z
dc.date.issued2006-05
dc.identifier.citationHoh, S.-T., Lim, M.C.C., Seah, S.K.L., Lim, A.T.H., Chew, S.-J., Foster, P.J., Aung, T. (2006-05). Peripapillary Retinal Nerve Fiber Layer Thickness Variations with Myopia. Ophthalmology 113 (5) : 773-777. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ophtha.2006.01.058
dc.identifier.issn01616420
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/132822
dc.description.abstractPurpose: To determine the relationship between peripapillary retinal nerve fiber layer (RNFL) thickness and myopia using optical coherence tomography (OCT). Design: Prospective observational case series. Methods: One hundred thirty-two young males with myopia (spherical equivalent [SE], -0.50 to -14.25 diopters) underwent ophthalmic examination of one randomly selected eye. Optical coherence tomography (OCT-1, version 4.1) was performed by a single operator using circular scans concentric with the optic disc with scan diameters of 3.40 mm, 4.50 mm, and 1.75 × vertical disc diameter (VDD). For each scan diameter, mean peripapillary RNFL thickness was calculated. Statistical analysis comprised repeated-measurements analysis and Pearson correlation. Results: Mean peripapillary RNFL thickness did not correlate with SE for the 3.40-mm (r = -0.11, P = 0.22), 4.50-mm (r = -0.103, P = 0.24), or 1.75×VDD (r = -0.08, P = 0.36) OCT scan diameters. Neither did mean peripapillary RNFL thickness correlate with axial length for the 3.40-mm (r = -0.04, P = 0.62), 4.50-mm (r = 0.03, P = 0.75), or 1.75×VDD (r = -0.02, P = 0.78) scan diameters. Mean peripapillary RNFL thicknesses for the 3.40-mm, 4.50-mm, and 1.75×VDD scans were 101.1±8.2 μm (95% confidence interval [CI], 99.4-102.8), 78.9±8.2 μm (95% CI, 77.5-80.3), and 97.5±10.9 μm (95% CI, 95.6-99.4), respectively. Conclusions: Mean peripapillary RNFL thickness did not vary with myopic SE or axial length for any OCT scan diameter investigated. Retinal NFL thickness measurements may be a useful parameter to assess and monitor glaucoma damage in myopic subjects. © 2006 American Academy of Ophthalmology.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.ophtha.2006.01.058
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1016/j.ophtha.2006.01.058
dc.description.sourcetitleOphthalmology
dc.description.volume113
dc.description.issue5
dc.description.page773-777
dc.description.codenOPHTD
dc.identifier.isiut000237263200010
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