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|Title:||Positive association between plasma homocysteine level and chronic kidney disease||Authors:||Shankar, A.
|Keywords:||Blue Mountains Eye Study
Chronic kidney disease
|Issue Date:||Feb-2008||Citation:||Shankar, A., Wang, J.J., Chua, B., Rochtchina, E., Flood, V., Mitchell, P. (2008-02). Positive association between plasma homocysteine level and chronic kidney disease. Kidney and Blood Pressure Research 31 (1) : 55-62. ScholarBank@NUS Repository. https://doi.org/10.1159/000114300||Abstract:||Background: Increasing experimental evidence, including recently developed animal models, supports a role for homocysteine in the development of chronic kidney disease (CKD). However, relatively few clinical/epidemiological studies have examined this hypothesis in humans. We examined the relationship between plasma homocysteine level and CKD in a population-based study of older Australians. Methods: Community-based study (1992-1994) among 2,609 individuals (58.6% women), aged 49-98 years, free of clinical cardiovascular disease in the Blue Mountains region, west of Sydney, Australia. The main outcome-of-interest was CKD (n = 461), defined as estimated glomerular filtration rate of 14 μmol/l) to quartile 1 (≤9 μmol/l) was 10.44 (6.99-15.60), p-trend||Source Title:||Kidney and Blood Pressure Research||URI:||http://scholarbank.nus.edu.sg/handle/10635/132789||ISSN:||14204096||DOI:||10.1159/000114300|
|Appears in Collections:||Staff Publications|
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