Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/132541
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dc.titleImmunogenetics of nasopharyngeal carcinoma. Position in 1980
dc.contributor.authorChan, S.H.
dc.date.accessioned2016-12-13T05:33:38Z
dc.date.available2016-12-13T05:33:38Z
dc.date.issued1980
dc.identifier.citationChan, S.H. (1980). Immunogenetics of nasopharyngeal carcinoma. Position in 1980. Annals of the Academy of Medicine Singapore 9 (3) : 296-299. ScholarBank@NUS Repository.
dc.identifier.issn03044602
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/132541
dc.description.abstractThe HLA profile of 313 newly diagnosed Chinese NPC patients was compared to that of 330 normal Chinese subjects. A2 Bw46 and Aw19/B B17 were associated with increased risks of developing NPC whereas A11 was associated with a decreased risk. A2 Bw46 was confined to older onset patients whereas Aw19/B B17 was associated with NPC patients of all ages but particularly with younger patients. The Aw19/B B17 haplotype was also associated with poor survival. A DR blank was strongly associated with NPC giving a relative risk of 26.5. In Malay NPC the HLA associations were Aw19/B B17 and A9 B18 and in Kadazan NPC, the association was with A9. Possible mechanisms of the HLA association were discussed.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentMICROBIOLOGY
dc.description.sourcetitleAnnals of the Academy of Medicine Singapore
dc.description.volume9
dc.description.issue3
dc.description.page296-299
dc.description.codenAAMSC
dc.identifier.isiutNOT_IN_WOS
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