Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/132541
Title: Immunogenetics of nasopharyngeal carcinoma. Position in 1980
Authors: Chan, S.H. 
Issue Date: 1980
Citation: Chan, S.H. (1980). Immunogenetics of nasopharyngeal carcinoma. Position in 1980. Annals of the Academy of Medicine Singapore 9 (3) : 296-299. ScholarBank@NUS Repository.
Abstract: The HLA profile of 313 newly diagnosed Chinese NPC patients was compared to that of 330 normal Chinese subjects. A2 Bw46 and Aw19/B B17 were associated with increased risks of developing NPC whereas A11 was associated with a decreased risk. A2 Bw46 was confined to older onset patients whereas Aw19/B B17 was associated with NPC patients of all ages but particularly with younger patients. The Aw19/B B17 haplotype was also associated with poor survival. A DR blank was strongly associated with NPC giving a relative risk of 26.5. In Malay NPC the HLA associations were Aw19/B B17 and A9 B18 and in Kadazan NPC, the association was with A9. Possible mechanisms of the HLA association were discussed.
Source Title: Annals of the Academy of Medicine Singapore
URI: http://scholarbank.nus.edu.sg/handle/10635/132541
ISSN: 03044602
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

11
checked on Nov 8, 2019

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.