Please use this identifier to cite or link to this item:
|dc.title||Metabolic, immunological and clinical characteristics in newly diagnosed Asian diabetes patients aged 12-40 years|
|dc.identifier.citation||Pan, C.Y., So, W.Y., Khalid, B.A.K., Mohan, V., Thai, A.C., Zimmet, P., Cockram, C.S., Jorgensen, L.N., Yeo, J.P. (2004-09). Metabolic, immunological and clinical characteristics in newly diagnosed Asian diabetes patients aged 12-40 years. Diabetic Medicine 21 (9) : 1007-1013. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1464-5491.2004.01287.x|
|dc.description.abstract||Aim: To describe the clinical, biochemical and immunological characteristics of young-onset diabetes in Asia. Methods: Clinical, biochemical and immunological variables were assessed in 919 newly diagnosed (duration less than 12 months) young onset Asian diabetic patients aged between 12 and 40 years. The subjects constituted 57% Chinese, 29% Indians and 14% Malays, recruited from diabetes centres in China, Hong Kong, India, Malaysia and Singapore. Results: The mean age (± SD) was 31.6 ± 7.2 years, with the majority (66%) in the 31-40 years age group. Mean body mass index (BMI) (± SD) was 25.3 ± 5.0 kg/m 2 with 47% exceeding the suggested Asian cut-off point for obesity (BMI > 25). Ethnic difference in clinical characteristics included BMI, blood pressure, mode of treatment and degree of insulin resistance. Most patients had a clinical presentation of Type 2 diabetes. About 10% had a classical combination of ketotic presentation, presence of autoimmune-markers and documented insulin deficiency indicative of Type 1 diabetes. Forty-eight percent were receiving oral hypoglycaemic agents (OHAs) while 31% were on diet only, 18% were receiving insulin and 2% were on a combination of insulin and OHA. Conclusion: Young onset diabetes patients in Asia represent a heterogenous group in terms of their clinical and biochemical characteristics and classical Type 1 diabetes is relatively uncommon. The 5-year follow up study will determine the progress of these patients and help to clarify the natural history.|
|Appears in Collections:||Staff Publications|
Show simple item record
Files in This Item:
There are no files associated with this item.
checked on Jan 31, 2023
WEB OF SCIENCETM
checked on Jan 24, 2023
checked on Feb 2, 2023
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.