Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1464-5491.2004.01287.x
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dc.titleMetabolic, immunological and clinical characteristics in newly diagnosed Asian diabetes patients aged 12-40 years
dc.contributor.authorPan, C.Y.
dc.contributor.authorSo, W.Y.
dc.contributor.authorKhalid, B.A.K.
dc.contributor.authorMohan, V.
dc.contributor.authorThai, A.C.
dc.contributor.authorZimmet, P.
dc.contributor.authorCockram, C.S.
dc.contributor.authorJorgensen, L.N.
dc.contributor.authorYeo, J.P.
dc.date.accessioned2016-12-13T05:33:33Z
dc.date.available2016-12-13T05:33:33Z
dc.date.issued2004-09
dc.identifier.citationPan, C.Y., So, W.Y., Khalid, B.A.K., Mohan, V., Thai, A.C., Zimmet, P., Cockram, C.S., Jorgensen, L.N., Yeo, J.P. (2004-09). Metabolic, immunological and clinical characteristics in newly diagnosed Asian diabetes patients aged 12-40 years. Diabetic Medicine 21 (9) : 1007-1013. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1464-5491.2004.01287.x
dc.identifier.issn07423071
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/132534
dc.description.abstractAim: To describe the clinical, biochemical and immunological characteristics of young-onset diabetes in Asia. Methods: Clinical, biochemical and immunological variables were assessed in 919 newly diagnosed (duration less than 12 months) young onset Asian diabetic patients aged between 12 and 40 years. The subjects constituted 57% Chinese, 29% Indians and 14% Malays, recruited from diabetes centres in China, Hong Kong, India, Malaysia and Singapore. Results: The mean age (± SD) was 31.6 ± 7.2 years, with the majority (66%) in the 31-40 years age group. Mean body mass index (BMI) (± SD) was 25.3 ± 5.0 kg/m 2 with 47% exceeding the suggested Asian cut-off point for obesity (BMI > 25). Ethnic difference in clinical characteristics included BMI, blood pressure, mode of treatment and degree of insulin resistance. Most patients had a clinical presentation of Type 2 diabetes. About 10% had a classical combination of ketotic presentation, presence of autoimmune-markers and documented insulin deficiency indicative of Type 1 diabetes. Forty-eight percent were receiving oral hypoglycaemic agents (OHAs) while 31% were on diet only, 18% were receiving insulin and 2% were on a combination of insulin and OHA. Conclusion: Young onset diabetes patients in Asia represent a heterogenous group in terms of their clinical and biochemical characteristics and classical Type 1 diabetes is relatively uncommon. The 5-year follow up study will determine the progress of these patients and help to clarify the natural history.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1111/j.1464-5491.2004.01287.x
dc.sourceScopus
dc.subjectAsians
dc.subjectAutoantibodies
dc.subjectC-peptide
dc.subjectDiabetes mellitus
dc.subjectInsulin deficient
dc.typeArticle
dc.contributor.departmentMEDICINE
dc.description.doi10.1111/j.1464-5491.2004.01287.x
dc.description.sourcetitleDiabetic Medicine
dc.description.volume21
dc.description.issue9
dc.description.page1007-1013
dc.description.codenDIMEE
dc.identifier.isiut000223405100009
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