Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0304-3940(98)00750-2
DC FieldValue
dc.titleTranssynaptic changes of neurons and associated microglial reaction in the spinal cord of rats following middle cerebral artery occlusion
dc.contributor.authorWu, Y.-P.
dc.contributor.authorLing, E.A.
dc.date.accessioned2016-11-29T02:51:35Z
dc.date.available2016-11-29T02:51:35Z
dc.date.issued1998-10-30
dc.identifier.citationWu, Y.-P., Ling, E.A. (1998-10-30). Transsynaptic changes of neurons and associated microglial reaction in the spinal cord of rats following middle cerebral artery occlusion. Neuroscience Letters 256 (1) : 41-44. ScholarBank@NUS Repository. https://doi.org/10.1016/S0304-3940(98)00750-2
dc.identifier.issn03043940
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/132042
dc.description.abstractThis study investigated transsynaptic neuronal damage and microglial reaction in the spinal cord contralateral to focal cerebral ischaemia in rats induced by permanent occlusion of the right middle cerebral artery (MCA). Three and five days after MCA occlusion, some neurons in the dorsal horn of lumbar spinal cord underwent degeneration and they appeared to be engulfed by reactive microglia; on the other hand, the ventral horn neurons remained ultrastructurally intact. It is suggested that the neuronal degeneration in the dorsal horn was attributed to deafferentation of the local neurons following ischaemic lesion of the corticospinal neurons which are the main source of afferent inputs.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/S0304-3940(98)00750-2
dc.sourceScopus
dc.subjectImmune-electron microscopy
dc.subjectMicroglial reaction
dc.subjectMiddle cerebral artery occlusion
dc.subjectSpinal neurons
dc.subjectTransneuronal degeneration
dc.typeArticle
dc.contributor.departmentORTHOPAEDIC SURGERY
dc.contributor.departmentANATOMY
dc.description.doi10.1016/S0304-3940(98)00750-2
dc.description.sourcetitleNeuroscience Letters
dc.description.volume256
dc.description.issue1
dc.description.page41-44
dc.description.codenNELED
dc.identifier.isiut000076992700011
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

27
checked on May 17, 2022

WEB OF SCIENCETM
Citations

25
checked on May 17, 2022

Page view(s)

68
checked on May 12, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.