Please use this identifier to cite or link to this item:
|Title:||Structural features of tracheal tube biofilm formed during prolonged mechanical ventilation||Authors:||Inglis, T.J.J.
confocal laser scanning microscopy
|Issue Date:||1995||Citation:||Inglis, T.J.J., Tit-Meng, L., Mah-Lee, N., Ee-Koon, T., Kok-Pheng, H. (1995). Structural features of tracheal tube biofilm formed during prolonged mechanical ventilation. Chest 108 (4) : 1049-1052. ScholarBank@NUS Repository.||Abstract:||The dissemination of tracheal tube biofilm into the mechanically ventilated lung has been proposed as a contributory factor in the pathogenesis of ventilator-associated pneumonia. In the present study, conventional light microscopy, confocal laser scanning microscopy, and scanning electron microscopy were used to examine luminal tracheal tube biofilm in tubes from ten consecutive medical intensive care patients. Biofilms also were cultured. No tube contained a predominantly microbial aggregate. Microorganisms were either dispersed throughout the biofilm or restricted to the most superficial layer. Neutrophil polymorphonuclear cells were present in all biofilms in a pattern suggesting that a layering or stratification had taken place. The distribution of neutrophils and microorganisms was consistent with a progressive accretion of respiratory secretions, rather than formation of a predominantly microbial biofilm.||Source Title:||Chest||URI:||http://scholarbank.nus.edu.sg/handle/10635/132034||ISSN:||00123692|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on May 22, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.