Please use this identifier to cite or link to this item:
|Title:||Ultrastructural Changes of Macroglial Cells in the Rat Brain Following an Exposure to a Non-penetrative Blast||Authors:||Kaur, C.
|Issue Date:||Jan-1997||Citation:||Kaur, C., Singh, J., Lim, M.K., Ng, B.L., Yap, E.P.H., Ling, E.A. (1997-01). Ultrastructural Changes of Macroglial Cells in the Rat Brain Following an Exposure to a Non-penetrative Blast. Annals of the Academy of Medicine Singapore 26 (1) : 27-29. ScholarBank@NUS Repository.||Abstract:||The present study examined the ultrastructural changes in astrocytes and oligodendrocytes in rats following an exposure to a nonpenetrative blast. At 1 and 7 days after the blast, the astrocytes in the cerebral and cerebellar cortex were hypertrophied; their end-feet associated with the blood vessels were also swollen, bearing sparsely distributed organelles. The above changes were not observed in experimental rats when the survival interval was prolonged. It is concluded from this study that the blast could have disrupted the integrity of the blood-brain barrier resulting in possible abnormal entry of serum-derived substances thereby leading to astrocyfic hypertrophy. The reversible nature of the changes is evidenced by the seemingly normal appearance of astrocytes in rats killed at 14, 21 and 28 days after the blast. Oligodendrocytes remained unaffected at various time intervals after the blast.||Source Title:||Annals of the Academy of Medicine Singapore||URI:||http://scholarbank.nus.edu.sg/handle/10635/131889||ISSN:||03044602|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.