Please use this identifier to cite or link to this item: https://doi.org/10.1021/np9700679
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dc.titleMichellamines D-F, new HIV-inhibitory dimeric naphthylisoquinoline alkaloids, and korupensamine E, a new antimalarial monomer, from Ancistrocladus korupensis
dc.contributor.authorHallock, Y.F.
dc.contributor.authorManfredi, K.P.
dc.contributor.authorDai, J.-R.
dc.contributor.authorCardellina II, J.H.
dc.contributor.authorGulakowski, R.J.
dc.contributor.authorMcMahon, J.B.
dc.contributor.authorSchäffer, M.
dc.contributor.authorStahl, M.
dc.contributor.authorGulden, K.-P.
dc.contributor.authorBringmann, G.
dc.contributor.authorFrançois, G.
dc.contributor.authorBoyd, M.R.
dc.date.accessioned2016-11-28T10:20:43Z
dc.date.available2016-11-28T10:20:43Z
dc.date.issued1997-07
dc.identifier.citationHallock, Y.F., Manfredi, K.P., Dai, J.-R., Cardellina II, J.H., Gulakowski, R.J., McMahon, J.B., Schäffer, M., Stahl, M., Gulden, K.-P., Bringmann, G., François, G., Boyd, M.R. (1997-07). Michellamines D-F, new HIV-inhibitory dimeric naphthylisoquinoline alkaloids, and korupensamine E, a new antimalarial monomer, from Ancistrocladus korupensis. Journal of Natural Products 60 (7) : 677-683. ScholarBank@NUS Repository. https://doi.org/10.1021/np9700679
dc.identifier.issn01633864
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/131478
dc.description.abstractNew monomeric (korupensamine E, 6) and dimeric (michellamines D-F, 7-9) naphthylisoquinoline alkaloids have been isolated from exracts of the tropical liana Ancistrocladus korupensis. Structures were determined by spectroanalytical methods, and stereochemistry was defined through NOE correlations, chemical degradation, and CD spectroscopy. Michellamines D-F exhibited in vitro HIV-inhibitory activity comparable to michellamine B, and korupensamine E exhibited in vitro antimalarial activity comparable to korupensamines A-D.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1021/np9700679
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCENTRE FOR NATURAL PRODUCT RESEARCH
dc.description.doi10.1021/np9700679
dc.description.sourcetitleJournal of Natural Products
dc.description.volume60
dc.description.issue7
dc.description.page677-683
dc.description.codenJNPRD
dc.identifier.isiutA1997XN71100005
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