Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.cub.2006.01.020
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dc.titlePolycomb group complexes self-regulate imprinting of the polycomb group gene MEDEA in Arabidopsis
dc.contributor.authorJullien, P.E.
dc.contributor.authorKatz, A.
dc.contributor.authorOliva, M.
dc.contributor.authorOhad, N.
dc.contributor.authorBerger, F.
dc.date.accessioned2016-11-28T10:20:12Z
dc.date.available2016-11-28T10:20:12Z
dc.date.issued2006-03-07
dc.identifier.citationJullien, P.E., Katz, A., Oliva, M., Ohad, N., Berger, F. (2006-03-07). Polycomb group complexes self-regulate imprinting of the polycomb group gene MEDEA in Arabidopsis. Current Biology 16 (5) : 486-492. ScholarBank@NUS Repository. https://doi.org/10.1016/j.cub.2006.01.020
dc.identifier.issn09609822
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/131434
dc.description.abstractFertilization in flowering plants initiates the development of the embryo and endosperm, which nurtures the embryo. A few genes subjected to imprinting are expressed in endosperm from their maternal allele, while their paternal allele remains silenced [1-3]. Imprinting of the FWA gene involves DNA methylation [4]. Mechanisms controlling imprinting of the Polycomb group (Pc-G) gene MEDEA (MEA) [5] are not yet fully understood [6-10]. Here we report that MEA imprinting is regulated by histone methylation. This epigenetic chromatin modification is mediated by several Pc-G activities during the entire plant life cycle. We show that Pc-G complexes maintain MEA transcription silenced throughout vegetative life and male gametogenesis. In endosperm, the maternal allele of MEA encodes an essential component of a Pc-G complex, which maintains silencing of the paternal MEA allele. Hence, we conclude that a feedback loop controls MEA imprinting. This feedback loop ensures a complete maternal control of MEA expression from both parental alleles and might have provided a template for evolution of imprinting in plants. ©2006 Elsevier Ltd All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.cub.2006.01.020
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.1016/j.cub.2006.01.020
dc.description.sourcetitleCurrent Biology
dc.description.volume16
dc.description.issue5
dc.description.page486-492
dc.description.codenCUBLE
dc.identifier.isiut000236056100024
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