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Title: HLA-DR antigen expression in intestinal-type and diffuse-type gastric carcinoma
Authors: Teh, M. 
Lee, Y.-S. 
Issue Date: 1992
Citation: Teh, M., Lee, Y.-S. (1992). HLA-DR antigen expression in intestinal-type and diffuse-type gastric carcinoma. Cancer 69 (5) : 1104-1107. ScholarBank@NUS Repository.
Abstract: The expression of the HLA-DR antigen, a Class II HLA antigen, was analyzed in 41 cases of gastric carcinoma (23 intestinal-type and 18 diffuse-type according to a modified Lauren classification) using a monoclonal antibody that is reactive to this antigen in routinely formalin-fixed, paraffin- embedded tissue sections. Seventeen cases of intestinal-type gastric carcinoma and two cases of diffuse-type gastric carcinoma were positive for the HLA-DR antigen. The staining in intestinal-type carcinoma generally was stronger and more extensive than in diffuse-type carcinoma, which showed only weak and focal staining. The difference in the frequency and pattern of staining between intestinal and diffuse-type gastric carcinoma supports the concept that these are two distinct subtypes of gastric carcinoma.
Source Title: Cancer
ISSN: 0008543X
Appears in Collections:Staff Publications

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