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Title: History and perspective of stem cell research
Authors: Bongso, A. 
Richards, M. 
Keywords: Adult stem cell
Embryonic stem cell
Reparative medicine
Stem cell
Issue Date: Dec-2004
Citation: Bongso, A., Richards, M. (2004-12). History and perspective of stem cell research. Best Practice and Research: Clinical Obstetrics and Gynaecology 18 (6) : 827-842. ScholarBank@NUS Repository.
Abstract: Several types of stem cell have been discovered from germ cells, the embryo, fetus and adult. Each of these has promised to revolutionize the future of regenerative medicine through the provision of cell-replacement therapies to treat a variety of debilitating diseases. Stem cell research is politically charged, receives considerable media coverage, raises many ethical and religious debates and generates a great deal of public interest. The tremendous versatility of embryonic stem cells versus the unprecedented reports describing adult stem cell plasticity have ignited debates as to the choice of one cell type over another for future application. However, the biology of these mysterious cells have yet to be understood and a lot more basic research is needed before new therapies using stem-cell-differentiated derivatives can be applied. Stem cell research opens-up the new field of 'cell-based therapies' and, as such, several safety measures have also to be evaluated. © 2004 Elsevier Ltd. All rights reserved.
Source Title: Best Practice and Research: Clinical Obstetrics and Gynaecology
ISSN: 15216934
DOI: 10.1016/j.bpobgyn.2004.09.002
Appears in Collections:Staff Publications

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