Haemostatic function changes in Singapore women using NORPLANT® implants: A four year review

Abstract

In this longitudinal study involving 100 Singaporean women, results indicate that the acceptors persist to have a possibly increased predisposition to thrombosis as evidenced by significant increases in platelet count and aggregability. Furthermore the shortened prothrombin time and activated partial thromboplastin time together with changes in vitamin K factors still indicate the possible enhanced potential for hypercoagulation.