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Title: Laryngeal mask insertion using thiopental and low dose atracurium: A comparison with propofol
Authors: Koh, K.F. 
Chen, F.G. 
Cheong, K.F. 
Esuvaranathan, V.
Issue Date: 1999
Citation: Koh, K.F., Chen, F.G., Cheong, K.F., Esuvaranathan, V. (1999). Laryngeal mask insertion using thiopental and low dose atracurium: A comparison with propofol. Canadian Journal of Anaesthesia 46 (7) : 670-674. ScholarBank@NUS Repository.
Abstract: Purpose: To compare the laryngeal mask airway (LMA) insertion conditions produced by propofol and a thiopental - low dose atracurium combination. Methods: In a randomized controlled double blind study, 120 premedicated patients were allocated into four groups. After pre-oxygenation, anesthesia was induced as follows: 1 μg · kg-1 fentanyl, 2.5 mg · kg-1 propofol (group I); 1 μg · kg-1 fentanyl, 5 mg · kg-1 thiopental (group II); 1 μg · kg-1 fentanyl, 5 mg · kg-1 thiopental, 0,05 mg · kg-1 or 0.1 mg · kg-1 atracurium (groups III and IV respectively). The LMA was inserted by a blinded anesthesiologist who also assessed the following insertion conditions on a three point scale; jaw relaxation, biting, gagging, coughing, presence of laryngospasm, adequacy of airway patency, number of attempts at insertion and overall insertion conditions. Results: There was no difference in insertion conditions between groups I, III and IV. Group II produced the worst overall conditions (P < 0.05). There were no differences in hemodynamic changes and apnea times between all four groups. Conclusion: The combination of fentanyl-thiopental with low dose atracurium (0.05 or 0.1 mg · kg-1) provided conditions comparable with those of propofol for LMA insertion.
Source Title: Canadian Journal of Anaesthesia
ISSN: 0832610X
Appears in Collections:Staff Publications

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