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Title: Inhalational induction with isoflurane: The influence of lidocaine pretreatment
Authors: Cheong, K.F. 
Khoo, S.T. 
Keywords: Induction
Issue Date: 1996
Citation: Cheong, K.F., Khoo, S.T. (1996). Inhalational induction with isoflurane: The influence of lidocaine pretreatment. Journal of Anesthesia 10 (2) : 125-128. ScholarBank@NUS Repository.
Abstract: The effect of intravenous lidocaine in reducing the incidence of complicated induction during a single vital capacity breath technique using isoflurane was studied. Forty patients were randomized into two groups to receive either placebo (group A) or intravenous lidocaine 1.5 -1 (group B) just prior to induction. Inhalational induction using 2% isoflurane and 66% nitrous oxide in oxygen was then carried out. Patients pretreated with lidocaine had significantly fewer complications during induction of anesthesia. Modest decreases in blood pressure and heart rate were observed in both groups but were clinically insignificant. Intravenous lidocaine pretreatment significantly reduced the incidence of complications during inhalational induction.
Source Title: Journal of Anesthesia
ISSN: 09138668
DOI: 10.1007/BF02483348
Appears in Collections:Staff Publications

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