Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/131111
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dc.titleMixed columnar cell and tall cell variant of papillary carcinoma of thyroid: A case report and review of the literature
dc.contributor.authorPutti, T.C.
dc.contributor.authorBhuiya, T.A.
dc.date.accessioned2016-11-28T10:16:22Z
dc.date.available2016-11-28T10:16:22Z
dc.date.issued2000
dc.identifier.citationPutti, T.C., Bhuiya, T.A. (2000). Mixed columnar cell and tall cell variant of papillary carcinoma of thyroid: A case report and review of the literature. Pathology 32 (4) : 286-289. ScholarBank@NUS Repository.
dc.identifier.issn00313025
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/131111
dc.description.abstractColumnar cell and tall cell carcinomas are newly described variants of papillary thyroid carcinoma associated with aggressive clinical behaviour. Although several cases of tall cell and columnar cell variants have been reported, only a single detailed case report of a mixed tall cell and columnar cell variant has been described in the English-language literature. We report another such composite tumour with predominant columna cell features in an elderly female. The tumour showed extrathyroidal extension with intraluminal superior thyroid vein invasion and lymph node metastasis. DNA ploidy analysis showed a diploid DNA content with no increase of S-phase fraction. Immunohistochemistry showed focal positivity for p53 and Ki-67 at the infiltrating margins of the turnout and diffuse positivity for proliferating cell nuclear antigen. The adverse clinical course warrants aggressive treatment and careful follow-up.
dc.sourceScopus
dc.subjectColumnar cell
dc.subjectPapillary thyroid carcinoma
dc.subjectTall cell
dc.typeArticle
dc.contributor.departmentPATHOLOGY
dc.description.sourcetitlePathology
dc.description.volume32
dc.description.issue4
dc.description.page286-289
dc.description.codenPTLGA
dc.identifier.isiutNOT_IN_WOS
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