Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/130928
DC Field | Value | |
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dc.title | L-asparaginase induced intracranial haemorrhage in acute lymphoblastic leukemia | |
dc.contributor.author | Lim, H.L. | |
dc.contributor.author | Teo, C.P. | |
dc.contributor.author | Wong, K. | |
dc.contributor.author | Kueh, Y.K. | |
dc.date.accessioned | 2016-11-28T10:14:16Z | |
dc.date.available | 2016-11-28T10:14:16Z | |
dc.date.issued | 1998-02 | |
dc.identifier.citation | Lim, H.L., Teo, C.P., Wong, K., Kueh, Y.K. (1998-02). L-asparaginase induced intracranial haemorrhage in acute lymphoblastic leukemia. Singapore Medical Journal 39 (2) : 76-78. ScholarBank@NUS Repository. | |
dc.identifier.issn | 00375675 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/130928 | |
dc.description.abstract | A 20-year-old national serviceman with acute lymphoblastic leukaemia, developed a large left parieto-occipital haemorrhage 7 days after completion of induction chemotherapy. Severe hypofibrinogenemia had been noted while he was receiving L-asparaginase. The haemorrhage could not be attributed to thrombocytopenia, disseminated intravascular coagulopathy, arterio-venous malformation, berry aneurysm or leukaemic infiltration because each of these causes was carefully investigated into and excluded. We conclude that the intracranial haemorrhage was likely L-asparaginase induced, an uncommon but recognised complication associated with L-asparaginase therapy. | |
dc.source | Scopus | |
dc.subject | Acute lymphoblastic leukaemia | |
dc.subject | Hypofibrinogenemia | |
dc.subject | Intracranial haemorrhage | |
dc.subject | L-asparaginase | |
dc.type | Article | |
dc.contributor.department | MEDICINE | |
dc.description.sourcetitle | Singapore Medical Journal | |
dc.description.volume | 39 | |
dc.description.issue | 2 | |
dc.description.page | 76-78 | |
dc.description.coden | SIMJA | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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